| Rational design of potent sialidase-based inhibitors of influenza virus replication M Von Itzstein, WY Wu, GB Kok, MS Pegg, JC Dyason, B Jin, T Van Phan, ... Nature 363 (6428), 418-423, 1993 | 2410 | 1993 |
| Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 Å resolution JN Varghese, WG Laver, PM Colman Nature 303 (5912), 35-40, 1983 | 1162 | 1983 |
| Structure of the catalytic and antigenic sites in influenza virus neuraminidase PM Colman, JN Varghese, WG Laver Nature 303 (5912), 41-44, 1983 | 1068 | 1983 |
| Three-dimensional structure of a complex of antibody with influenza virus neuraminidase PM Colman, WG Laver, JN Varghese, AT Baker, PA Tulloch, GM Air, ... Nature 326 (6111), 358-363, 1987 | 723 | 1987 |
| The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor JN Varghese, JL McKimm‐Breschkin, JB Caldwell, AA Kortt, PM Colman Proteins: Structure, Function, and Bioinformatics 14 (3), 327-332, 1992 | 523 | 1992 |
| Three-dimensional structure of the neuraminidase of influenza virus A/Tokyo/3/67 at 2· 2 Å resolution JN Varghese, PM Colman Journal of molecular biology 221 (2), 473-486, 1991 | 313 | 1991 |
| Three-dimensional structure of a barley β-D-glucan exohydrolase, a family 3 glycosyl hydrolase JN Varghese, M Hrmova, GB Fincher Structure 7 (2), 179-190, 1999 | 296 | 1999 |
| Refined crystal structure of the influenza virus N9 neuraminidase-NC41 Fab complex WR Tulip, JN Varghese, WG Laver, RG Webster, PM Colman Journal of molecular biology 227 (1), 122-148, 1992 | 266 | 1992 |
| Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase JN Varghese, PW Smith, SL Sollis, TJ Blick, A Sahasrabudhe, ... Structure 6 (6), 735-746, 1998 | 265 | 1998 |
| Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4 … NR Taylor, A Cleasby, O Singh, T Skarzynski, AJ Wonacott, PW Smith, ... Journal of medicinal chemistry 41 (6), 798-807, 1998 | 265 | 1998 |
| Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III MC Lawrence, NA Borg, VA Streltsov, PA Pilling, VC Epa, JN Varghese, ... Journal of molecular biology 335 (5), 1343-1357, 2004 | 261 | 2004 |
| Three‐dimensional structure of the complex of 4‐guanidino‐Neu5Ac2en and influenza virus neuraminidase JN Varghese, V Chandana Epa, PM Colman Protein science 4 (6), 1081-1087, 1995 | 258 | 1995 |
| Three-dimensional structures of two plant beta-glucan endohydrolases with distinct substrate specificities. JN Varghese, TP Garrett, PM Colman, L Chen, PB Høj, GB Fincher Proceedings of the National Academy of Sciences 91 (7), 2785-2789, 1994 | 247 | 1994 |
| Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors JL McKimm-Breschkin, A Sahasrabudhe, TJ Blick, M McDonald, ... Journal of virology 72 (3), 2456-2462, 1998 | 246 | 1998 |
| The three‐dimensional structure of the seed storage protein phaseolin at 3 A resolution. MC Lawrence, E Suzuki, JN Varghese, PC Davis, A Van Donkelaar, ... The EMBO journal 9 (1), 9-15, 1990 | 200 | 1990 |
| Structural evidence for evolution of shark Ig new antigen receptor variable domain antibodies from a cell-surface receptor VA Streltsov, JN Varghese, JA Carmichael, RA Irving, PJ Hudson, ... Proceedings of the National Academy of Sciences 101 (34), 12444-12449, 2004 | 188 | 2004 |
| Structural studies of the resistance of influenza virus neuramindase to inhibitors BJ Smith, JL McKimm-Breshkin, M McDonald, RT Fernley, JN Varghese, ... Journal of medicinal chemistry 45 (11), 2207-2212, 2002 | 175 | 2002 |
| Generation and characterization of an influenza virus neuraminidase variant with decreased sensitivity to the neuraminidase-specific inhibitor 4-guanidino-Neu5Ac2en TJ BLICK, TAK Tiong, A SAHASRABUDHE, JN VARGHESE, ... Virology 214 (2), 475-484, 1995 | 175 | 1995 |
| Cardiovascular biology of interleukin-6 MY Abeywardena, WR Leifert, KE Warnes, JN Varghese, RJ Head Current pharmaceutical design 15 (15), 1809-1821, 2009 | 167 | 2009 |
| Structural evidence for a second sialic acid binding site in avian influenza virus neuraminidases JN Varghese, PM Colman, A Van Donkelaar, TJ Blick, A Sahasrabudhe, ... Proceedings of the National Academy of Sciences 94 (22), 11808-11812, 1997 | 165 | 1997 |
