Jose Varghese
Jose Varghese
Retired, Chief Research Scientist, C.S.I.R.O. Australia
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JudulDikutip olehTahun
Rational design of potent sialidase-based inhibitors of influenza virus replication
M von Itzstein, WY Wu, GB Kok, MS Pegg, JC Dyason, B Jin, T Van Phan, ...
Nature 363 (6428), 418, 1993
19601993
Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 resolution
JN Varghese, WG Laver, PM Colman
Nature 303 (5912), 35, 1983
9601983
Structure of the catalytic and antigenic sites in influenza virus neuraminidase
PM Colman, JN Varghese, WG Laver
Nature 303 (5912), 41, 1983
8911983
Three-dimensional structure of a complex of antibody with influenza virus neuraminidase
PM Colman, WG Laver, JN Varghese, AT Baker, PA Tulloch, GM Air, ...
Nature 326 (6111), 358, 1987
6231987
The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor
JN Varghese, JL McKimm‐Breschkin, JB Caldwell, AA Kortt, PM Colman
Proteins: Structure, Function, and Bioinformatics 14 (3), 327-332, 1992
4471992
Three-dimensional structure of the neuraminidase of influenza virus A/Tokyo/3/67 at 2 2 resolution
JN Varghese, PM Colman
Journal of molecular biology 221 (2), 473-486, 1991
2641991
Three-dimensional structure of a barley β-D-glucan exohydrolase, a family 3 glycosyl hydrolase
JN Varghese, M Hrmova, GB Fincher
Structure 7 (2), 179-190, 1999
2371999
Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4…
NR Taylor, A Cleasby, O Singh, T Skarzynski, AJ Wonacott, PW Smith, ...
Journal of medicinal chemistry 41 (6), 798-807, 1998
2331998
Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase
JN Varghese, PW Smith, SL Sollis, TJ Blick, A Sahasrabudhe, ...
Structure 6 (6), 735-746, 1998
2291998
Refined crystal structure of the influenza virus N9 neuraminidase-NC41 Fab complex
WR Tulip, JN Varghese, WG Laver, RG Webster, PM Colman
Journal of molecular biology 227 (1), 122-148, 1992
2251992
Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors
JL McKimm-Breschkin, A Sahasrabudhe, TJ Blick, M McDonald, ...
Journal of virology 72 (3), 2456-2462, 1998
2201998
Three‐dimensional structure of the complex of 4‐guanidino‐Neu5Ac2en and influenza virus neuraminidase
JN Varghese, V Chandana Epa, PM Colman
Protein science 4 (6), 1081-1087, 1995
2181995
Three-dimensional structures of two plant beta-glucan endohydrolases with distinct substrate specificities
JN Varghese, TP Garrett, PM Colman, L Chen, PB Hj, GB Fincher
Proceedings of the National Academy of Sciences 91 (7), 2785-2789, 1994
2071994
Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III
MC Lawrence, NA Borg, VA Streltsov, PA Pilling, VC Epa, JN Varghese, ...
Journal of molecular biology 335 (5), 1343-1357, 2004
2042004
The three‐dimensional structure of the seed storage protein phaseolin at 3 A resolution.
MC Lawrence, E Suzuki, JN Varghese, PC Davis, A Van Donkelaar, ...
The EMBO journal 9 (1), 9-15, 1990
1761990
Generation and characterization of an influenza virus neuraminidase variant with decreased sensitivity to the neuraminidase-specific inhibitor 4-guanidino-Neu5Ac2en
TJ Blick, T Tiong, A Sahasrabudhe, JN Varghese, PM Colman, GJ Hart, ...
Virology 214 (2), 475-484, 1995
1651995
Structural studies of the resistance of influenza virus neuramindase to inhibitors
BJ Smith, JL McKimm-Breshkin, M McDonald, RT Fernley, JN Varghese, ...
Journal of medicinal chemistry 45 (11), 2207-2212, 2002
1432002
Structural evidence for evolution of shark Ig new antigen receptor variable domain antibodies from a cell-surface receptor
VA Streltsov, JN Varghese, JA Carmichael, RA Irving, PJ Hudson, ...
Proceedings of the National Academy of Sciences 101 (34), 12444-12449, 2004
1392004
Cardiovascular biology of interleukin-6
MY Abeywardena, WR Leifert, KE Warnes, JN Varghese, RJ Head
Current pharmaceutical design 15 (15), 1809-1821, 2009
1332009
Three‐dimensional structure of neuraminidase of subtype N9 from an avian influenza virus
AT Baker, JN Varghese, WG Laver, GM Air, PM Colman
Proteins: Structure, Function, and Bioinformatics 2 (2), 111-117, 1987
1251987
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