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Peter Olinga
Peter Olinga
Professor of Translational Biopharmaceutics, University of Groningen
Verified email at rug.nl - Homepage
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Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating …
P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ...
Archives of toxicology 87, 1315-1530, 2013
13922013
Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies
IAM De Graaf, P Olinga, MH De Jager, MT Merema, R De Kanter, ...
Nature protocols 5 (9), 1540-1551, 2010
4632010
Procalcitonin behaves as a fast responding acute phase proteinin vivoandin vitro
MWN Nijsten, P Olinga, EGE de Vries, HS Koops, GMM Groothuis, ...
Critical care medicine 28 (2), 458-461, 2000
4552000
LPS-induced downregulation of MRP2 and BSEP in human liver is due to a posttranscriptional process
MGL Elferink, P Olinga, AL Draaisma, MT Merema, KN Faber, MJH Slooff, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 287 (5 …, 2004
2302004
Targeting oxidative stress for the treatment of liver fibrosis
T Luangmonkong, S Suriguga, HAM Mutsaers, GMM Groothuis, P Olinga, ...
Reviews of Physiology, Biochemistry and Pharmacology, Vol. 175, 71-102, 2018
2262018
Albumin Modified With Mannose 6–Phosphate: A Potential Carrier for Selective Delivery of Antifibrotic Drugs to Rat and Human Hepatic Stellate Cells
L Beljaars, G Molema, B Weert, H Bonnema, P Olinga, GM Groothuis, ...
Hepatology 29 (5), 1486-1493, 1999
2221999
Precision-cut tissue slices as a tool to predict metabolism of novel drugs
IAM Graaf, GMM Groothuis, P Olinga
Expert opinion on drug metabolism & toxicology 3 (6), 879-898, 2007
1752007
Targeting dexamethasone to Kupffer cells: effects on liver inflammation and fibrosis in rats
BN Melgert, P Olinga, JMS Van Der Laan, B Weert, J Cho, D Schuppan, ...
Hepatology 34 (4), 719-728, 2001
1472001
Comparison of five incubation systems for rat liver slices using functional and viability parameters
P Olinga, K Groen, IH Hof, R De Kanter, HJ Koster, WR Leeman, ...
Journal of pharmacological and toxicological methods 38 (2), 59-69, 1997
1381997
Precision-cut liver slices: a tool to model the liver ex vivo
P Olinga, D Schuppan
Journal of hepatology 58 (6), 1252-1253, 2013
1322013
Liver slices in in vitro pharmacotoxicology with special reference to the use of human liver tissue
P Olinga, DKF Meijer, MJH Slooff, GMM Groothuis
Toxicology in vitro 12 (1), 77-100, 1997
1241997
Precision-cut liver slices as a new model to study toxicity-induced hepatic stellate cell activation in a physiologic milieu
M Van de Bovenkamp, GMM Groothuis, AL Draaisma, MT Merema, ...
Toxicological Sciences 85 (1), 632-638, 2005
1232005
Rat liver slices as a tool to study LPS-induced inflammatory response in the liver
P Olinga, MT Merema, MH De Jager, F Derks, BN Melgert, H Moshage, ...
Journal of hepatology 35 (2), 187-194, 2001
1232001
Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity
MGL Elferink, P Olinga, AL Draaisma, MT Merema, S Bauerschmidt, ...
Toxicology and applied pharmacology 229 (3), 300-309, 2008
1182008
Liver fibrosis in vitro: cell culture models and precision-cut liver slices
M Van de Bovenkamp, GMM Groothuis, DKF Meijer, P Olinga
Toxicology in vitro 21 (4), 545-557, 2007
1182007
Prostaglandin E2 inhibits transforming growth factor β1-mediated induction of collagen α1 (I) in hepatic stellate cells
AY Hui, AJ Dannenberg, JJY Sung, K Subbaramaiah, B Du, P Olinga, ...
Journal of hepatology 41 (2), 251-258, 2004
1122004
Drug-metabolizing activity of human and rat liver, lung, kidney and intestine slices
R De Kanter, MH De Jager, AL Draaisma, JU Jurva, P Olinga, DKF Meijer, ...
Xenobiotica 32 (5), 349-362, 2002
1122002
Coordinated induction of drug transporters and phase I and II metabolism in human liver slices
P Olinga, MGL Elferink, AL Draaisma, MT Merema, JV Castell, G Perez, ...
European journal of pharmaceutical sciences 33 (4-5), 380-389, 2008
1102008
Novel biotransformation and physiological properties of norursodeoxycholic acid in humans
AF Hofmann, SF Zakko, M Lira, C Clerici, LR Hagey, KK Lambert, ...
Hepatology 42 (6), 1391-1398, 2005
1092005
Effect of human liver source on the functionality of isolated hepatocytes and liver slices
P Olinga, M Merema, IH Hof, KP de Jong, MJH Slooff, DKF Meijer, ...
Drug Metabolism and Disposition 26 (1), 5-11, 1998
1091998
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