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Kenneth Pfarr
Kenneth Pfarr
University Hospital Bonn
Verified email at ukbonn.de - Homepage
Title
Cited by
Cited by
Year
Towards the sustainable discovery and development of new antibiotics
M Miethke, M Pieroni, T Weber, M Brönstrup, P Hammann, L Halby, ...
Nat Rev Chem 5, 726-749, 2021
5612021
Comparative genomics of the major parasitic worms
IHG Consortium
Nature Genetics, 2018
372*2018
Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study
A Hoerauf, S Specht, M Büttner, K Pfarr, S Mand, R Fimmers, ...
Medical microbiology and immunology 197, 295-311, 2008
3072008
Doxycycline reduces plasma VEGF-C/sVEGFR-3 and improves pathology in lymphatic filariasis
AY Debrah, S Mand, S Specht, Y Marfo-Debrekyei, L Batsa, K Pfarr, ...
PLoS pathogens 2 (9), e92, 2006
2382006
Doxycycline as a novel strategy against bancroftian filariasis—depletion of Wolbachia endosymbionts from Wuchereria bancrofti and stop of microfilaria production
A Hoerauf, S Mand, K Fischer, T Kruppa, Y Marfo-Debrekyei, AY Debrah, ...
Medical microbiology and immunology 192, 211-216, 2003
2312003
Filariasis and lymphoedema
KM Pfarr, AY Debrah, S Specht, A Hoerauf
Parasite immunology 31 (11), 664-672, 2009
2072009
Filariasis in Africa—treatment challenges and prospects
A Hoerauf, K Pfarr, S Mand, AY Debrah, S Specht
Clinical Microbiology and Infection 17 (7), 977-985, 2011
1702011
Macrofilaricidal effect of 4 weeks of treatment with doxycycline on Wuchereria bancrofti
AY Debrah, S Mand, Y Marfo‐Debrekyei, L Batsa, K Pfarr, M Buttner, ...
Tropical Medicine & International Health 12 (12), 1433-1441, 2007
1472007
A Randomized, Double-Blind Clinical Trial of a 3-Week Course of Doxycycline plus Albendazole and Ivermectin for the Treatment of Wuchereria bancrofti Infection
JD Turner, S Mand, AY Debrah, J Muehlfeld, K Pfarr, HF McGarry, O Adjei, ...
Clinical Infectious Diseases 42 (8), 1081-1089, 2006
1402006
Extracellular Onchocerca-derived small RNAs in host nodules and blood
JF Quintana, BL Makepeace, SA Babayan, A Ivens, KM Pfarr, M Blaxter, ...
Parasites & vectors 8, 1-11, 2015
1292015
Evidence against Wolbachia symbiosis in Loa loa
HF McGarry, K Pfarr, G Egerton, A Hoerauf, JP Akue, P Enyong, S Wanji, ...
Filaria journal 2, 1-7, 2003
1192003
Doxycycline Treatment of Brugia malayi—Infected Persons Reduces Microfilaremia and Adverse Reactions after Diethylcarbamazine and Albendazole Treatment
T Supali, Y Djuardi, KM Pfarr, H Wibowo, MJ Taylor, A Hoerauf, ...
Clinical infectious diseases 46 (9), 1385-1393, 2008
1142008
Plasma vascular endothelial growth Factor-A (VEGF-A) and VEGF-A gene polymorphism are associated with hydrocele development in lymphatic filariasis
AY Debrah, S Mand, MR Toliat, Y Marfo-Debrekyei, L Batsa, P Nürnberg, ...
American Journal of Tropical Medicine and Hygiene 77 (4), 601, 2007
922007
Functional conservation of the lipid II biosynthesis pathway in the cell wall‐less bacteria Chlamydia and Wolbachia: why is lipid II needed?
B Henrichfreise, A Schiefer, T Schneider, E Nzukou, C Poellinger, ...
Molecular microbiology 73 (5), 913-923, 2009
912009
Macrofilaricidal activity and amelioration of lymphatic pathology in bancroftian filariasis after 3 weeks of doxycycline followed by single-dose diethylcarbamazine
S Mand, K Pfarr, PK Sahoo, AK Satapathy, S Specht, U Klarmann, ...
The American journal of tropical medicine and hygiene, 2009
912009
Reduction in levels of plasma vascular endothelial growth factor-A and improvement in hydrocele patients by targeting endosymbiotic Wolbachia sp. in Wuchereria bancrofti with …
AY Debrah, S Mand, Y Marfo-Debrekyei, L Batsa, K Pfarr, B Lawson, ...
The American journal of tropical medicine and hygiene 80 (6): 956-63, 2009
812009
Antibiotic chemotherapy of onchocerciasis: in a bovine model, killing of adult parasites requires a sustained depletion of endosymbiotic bacteria (Wolbachia species)
J Gilbert, CK Nfon, BL Makepeace, LM Njongmeta, IM Hastings, KM Pfarr, ...
The Journal of infectious diseases 192 (8), 1483-1493, 2005
812005
Corallopyronin A Specifically Targets and Depletes Essential Obligate Wolbachia Endobacteria From Filarial Nematodes In Vivo
A Schiefer, A Schmitz, TF Schäberle, S Specht, C Lämmer, KL Johnston, ...
The Journal of infectious diseases 206 (2), 249-257, 2012
782012
Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis
KL Johnston, L Ford, I Umareddy, S Townson, S Specht, K Pfarr, ...
International Journal for Parasitology: Drugs and Drug Resistance 4 (3), 278-286, 2014
712014
Mitochondrial genes for heme-dependent respiratory chain complexes are up-regulated after depletion of Wolbachia from filarial nematodes
U Strübing, R Lucius, A Hoerauf, KM Pfarr
International journal for parasitology 40 (10), 1193-1202, 2010
672010
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Articles 1–20