| Fasciola hepatica cathepsin L-like proteases: biology, function, and potential in the development of first generation liver fluke vaccines JP Dalton, SO Neill, C Stack, P Collins, A Walshe, M Sekiya, S Doyle, ... International journal for parasitology 33 (11), 1173-1181, 2003 | 327 | 2003 |
| Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages S Donnelly, CM Stack, SM O'Neill, AA Sayed, DL Williams, JP Dalton The FASEB Journal 22 (11), 4022, 2008 | 271 | 2008 |
| Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propeptide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells PR Collins, CM Stack, SM O'Neill, S Doyle, T Ryan, GP Brennan, ... Journal of Biological Chemistry 279 (17), 17038-17046, 2004 | 192 | 2004 |
| Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase S McGowan, CJ Porter, J Lowther, CM Stack, SJ Golding, ... Proceedings of the National Academy of Sciences 106 (8), 2537-2542, 2009 | 179 | 2009 |
| Helminth cysteine proteases inhibit TRIF-dependent activation of macrophages via degradation of TLR3 S Donnelly, SM O’Neill, CM Stack, MW Robinson, L Turnbull, ... Journal of Biological Chemistry 285 (5), 3383-3392, 2010 | 168 | 2010 |
| Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase: a protease involved in amino acid regulation with potential for antimalarial drug development CM Stack, J Lowther, E Cunningham, S Donnelly, DL Gardiner, ... Journal of Biological Chemistry 282 (3), 2069-2080, 2007 | 159 | 2007 |
| Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials TS Skinner-Adams, CM Stack, KR Trenholme, CL Brown, J Grembecka, ... Trends in biochemical sciences 35 (1), 53-61, 2010 | 156 | 2010 |
| Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: expansion of a repertoire of virulence-associated factors MW Robinson, JF Tort, J Lowther, SM Donnelly, E Wong, W Xu, CM Stack, ... Molecular & Cellular Proteomics 7 (6), 1111-1123, 2008 | 156 | 2008 |
| Protection of cattle against a natural infection of Fasciola hepatica by vaccination with recombinant cathepsin L1 (rFhCL1) O Golden, RJ Flynn, C Read, M Sekiya, SM Donnelly, C Stack, JP Dalton, ... Vaccine 28 (34), 5551-5557, 2010 | 140 | 2010 |
| Leucine aminopeptidase of the human blood flukes, Schistosoma mansoni and Schistosoma japonicum E McCarthy, C Stack, SM Donnelly, S Doyle, VH Mann, PJ Brindley, ... International journal for parasitology 34 (6), 703-714, 2004 | 119 | 2004 |
| Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica CM Stack, CR Caffrey, SM Donnelly, A Seshaadri, J Lowther, JF Tort, ... Journal of Biological Chemistry 283 (15), 9896-9908, 2008 | 112 | 2008 |
| Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compounds TS Skinner-Adams, J Lowther, F Teuscher, CM Stack, J Grembecka, ... Journal of medicinal chemistry 50 (24), 6024-6031, 2007 | 109 | 2007 |
| Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases S McGowan, CA Oellig, WA Birru, TT Caradoc-Davies, CM Stack, ... Proceedings of the National Academy of Sciences 107 (6), 2449-2454, 2010 | 100 | 2010 |
| The Importance of pH in Regulating the Function of the Fasciola hepatica Cathepsin L1 Cysteine Protease J Lowther, MW Robinson, SM Donnelly, W Xu, CM Stack, JM Matthews, ... PLoS neglected tropical diseases 3 (1), e369, 2009 | 91 | 2009 |
| Overexpression of leucyl aminopeptidase in Plasmodium falciparum parasites: target for the antimalarial activity of bestatin DL Gardiner, KR Trenholme, TS Skinner-Adams, CM Stack, JP Dalton Journal of Biological Chemistry 281 (3), 1741-1745, 2006 | 79 | 2006 |
| Comparative analysis of Tritrichomonas foetus (Riedmüller, 1928) cat genotype, T. foetus (Riedmüller, 1928) cattle genotype and Tritrichomonas suis (Davaine, 1875) at 10 DNA loci J Šlapeta, N Müller, CM Stack, G Walker, A Lew-Tabor, J Tachezy, ... International journal for parasitology 42 (13-14), 1143-1149, 2012 | 73 | 2012 |
| The M18 aspartyl aminopeptidase of the human malaria parasite Plasmodium falciparum F Teuscher, J Lowther, TS Skinner-Adams, T Spielmann, MWA Dixon, ... Journal of Biological Chemistry 282 (42), 30817-30826, 2007 | 67 | 2007 |
| The M17 Leucine Aminopeptidase of the Malaria Parasite Plasmodium falciparum: Importance of Active Site Metal Ions in the Binding of Substrates and Inhibitors S Maric, SM Donnelly, MW Robinson, T Skinner-Adams, KR Trenholme, ... Biochemistry 48 (23), 5435-5439, 2009 | 60 | 2009 |
| Biochemical characterisation of the recombinant peroxiredoxin (FhePrx) of the liver fluke, Fasciola hepatica M Sekiya, G Mulcahy, JA Irwin, CM Stack, SM Donnelly, W Xu, P Collins, ... FEBS letters 580 (21), 5016-5022, 2006 | 57 | 2006 |
| The aminopeptidase inhibitor CHR-2863 is an orally bioavailable inhibitor of murine malaria TS Skinner-Adams, CL Peatey, K Anderson, KR Trenholme, D Krige, ... Antimicrobial agents and chemotherapy 56 (6), 3244-3249, 2012 | 55 | 2012 |
