Inflammasome is a central player in the induction of obesity and insulin resistance R Stienstra, JA Van Diepen, CJ Tack, MH Zaki, FL Van De Veerdonk, ... Proceedings of the National Academy of Sciences 108 (37), 15324-15329, 2011 | 766 | 2011 |
The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity R Stienstra, LAB Joosten, T Koenen, B Van Tits, JA Van Diepen, ... Cell metabolism 12 (6), 593-605, 2010 | 679 | 2010 |
Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit Z Li, CX Yi, S Katiraei, S Kooijman, E Zhou, CK Chung, Y Gao, ... Gut 67 (7), 1269-1279, 2018 | 507 | 2018 |
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development JFP Berbée, MR Boon, PPSJ Khedoe, A Bartelt, C Schlein, A Worthmann, ... Nature communications 6 (1), 6356, 2015 | 473 | 2015 |
ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis FG Schaap, PCN Rensen, PJ Voshol, C Vrins, HN van der Vliet, ... Journal of biological chemistry 279 (27), 27941-27947, 2004 | 390 | 2004 |
Interactions between inflammation and lipid metabolism: relevance for efficacy of anti-inflammatory drugs in the treatment of atherosclerosis JA van Diepen, JFP Berbée, LM Havekes, PCN Rensen Atherosclerosis 228 (2), 306-315, 2013 | 297 | 2013 |
Recombinant lipoproteins: lipoprotein-like lipid particles for drug targeting PCN Rensen, RLA de Vrueh, J Kuiper, MK Bijsterbosch, EAL Biessen, ... Advanced drug delivery reviews 47 (2-3), 251-276, 2001 | 278 | 2001 |
Cholesteryl Ester Transfer Protein Decreases High-Density Lipoprotein and Severely Aggravates Atherosclerosis in APOE*3-Leiden Mice M Westerterp, CC van der Hoogt, W de Haan, EH Offerman, ... Arteriosclerosis, thrombosis, and vascular biology 26 (11), 2552-2559, 2006 | 277 | 2006 |
Cryo-electron microscopy of extracellular vesicles in fresh plasma Y Yuana, RI Koning, ME Kuil, PCN Rensen, AJ Koster, RM Bertina, ... Journal of extracellular vesicles 2 (1), 21494, 2013 | 274 | 2013 |
Determination of the upper size limit for uptake and processing of ligands by the asialoglycoprotein receptor on hepatocytesin vitro and in vivo PCN Rensen, LAJM Sliedregt, M Ferns, E Kieviet, SMW Van Rossenberg, ... Journal of biological chemistry 276 (40), 37577-37584, 2001 | 252 | 2001 |
Apolipoprotein E protects against bacterial lipopolysaccharide-induced lethality: a new therapeutic approach to treat gram-negative sepsis M Van Oosten, PCN Rensen, ES Van Amersfoort, M Van Eck, ... Journal of Biological Chemistry 276 (12), 8820-8824, 2001 | 225 | 2001 |
Human brown adipocyte thermogenesis is driven by β2-AR stimulation DP Blondin, S Nielsen, EN Kuipers, MC Severinsen, VH Jensen, S Miard, ... Cell metabolism 32 (2), 287-300. e7, 2020 | 223 | 2020 |
Selective liver targeting of antivirals by recombinant chylomicrons—a new therapeutic approach to hepatitis B PCN Rensen, MCM Van Dijk, EC Havenaar, MK Bijsterbosch, JK Kruijt, ... Nature medicine 1 (3), 221-225, 1995 | 221 | 1995 |
Niacin Increases HDL by Reducing Hepatic Expression and Plasma Levels of Cholesteryl Ester Transfer Protein in APOE*3Leiden.CETP Mice JWA van der Hoorn, W de Haan, JFP Berbée, LM Havekes, JW Jukema, ... Arteriosclerosis, thrombosis, and vascular biology 28 (11), 2016-2022, 2008 | 220 | 2008 |
Angptl4 upregulates cholesterol synthesis in liver via inhibition of LPL-and HL-dependent hepatic cholesterol uptake L Lichtenstein, JFP Berbée, SJ van Dijk, KW van Dijk, A Bensadoun, ... Arteriosclerosis, thrombosis, and vascular biology 27 (11), 2420-2427, 2007 | 208 | 2007 |
Brown adipose tissue takes up plasma triglycerides mostly after lipolysis PPSJ Khedoe, G Hoeke, S Kooijman, W Dijk, JT Buijs, S Kersten, ... Journal of lipid research 56 (1), 51-59, 2015 | 205 | 2015 |
Role of brown fat in lipoprotein metabolism and atherosclerosis G Hoeke, S Kooijman, MR Boon, PCN Rensen, JFP Berbée Circulation research 118 (1), 173-182, 2016 | 198 | 2016 |
Particle size determines the specificity of apolipoprotein E-containing triglyceride-rich emulsions for the LDL receptor versus hepatic remnant receptor in vivo PC Rensen, N Herijgers, MH Netscher, SC Meskers, M van Eck, ... Journal of lipid research 38 (6), 1070-1084, 1997 | 194 | 1997 |
Apolipoproteins modulate the inflammatory response to lipopolysaccharide JFP Berbee, LM Havekes, PCN Rensen Journal of Endotoxin Research 11 (2), 97-103, 2005 | 188 | 2005 |
Design and synthesis of novel amphiphilic dendritic galactosides for selective targeting of liposomes to the hepatic asialoglycoprotein receptor LAJM Sliedregt, PCN Rensen, ET Rump, PJ van Santbrink, ... Journal of Medicinal Chemistry 42 (4), 609-618, 1999 | 188 | 1999 |