| Butyrate Greatly Enhances Derivation of Human Induced Pluripotent Stem Cells by Promoting Epigenetic Remodeling and the Expression of Pluripotency‐Associated Genes P Mali, BK Chou, J Yen, Z Ye, J Zou, S Dowey, RA Brodsky, JE Ohm, ... Stem Cells 28 (4), 713-720, 2010 | 500 | 2010 |
| Generation of induced pluripotent stem cells in the absence of drug selection R Blelloch, M Venere, J Yen, M Ramalho-Santos Cell Stem Cell 1 (3), 245-247, 2007 | 352 | 2007 |
| Selective in vivo metabolic cell-labeling-mediated cancer targeting H Wang, R Wang, K Cai, H He, Y Liu, J Yen, Z Wang, M Xu, Y Sun, ... Nature chemical biology 13 (4), 415-424, 2017 | 193 | 2017 |
| Directed evolution of adenine base editors with increased activity and therapeutic application NM Gaudelli, DK Lam, HA Rees, NM Solá-Esteves, LA Barrera, DA Born, ... Nature biotechnology 38 (7), 892-900, 2020 | 179 | 2020 |
| Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells JE Ohm, P Mali, L Van Neste, DM Berman, L Liang, K Pandiyan, ... Cancer research 70 (19), 7662-7673, 2010 | 92 | 2010 |
| Non-invasive, real-time reporting drug release in vitro and in vivo Y Zhang, Q Yin, J Yen, J Li, H Ying, H Wang, Y Hua, EJ Chaney, ... Chemical Communications 51 (32), 6948-6951, 2015 | 42 | 2015 |
| Base editing of haematopoietic stem cells rescues sickle cell disease in mice GA Newby, JS Yen, KJ Woodard, T Mayuranathan, CR Lazzarotto, Y Li, ... Nature 595 (7866), 295-302, 2021 | 37 | 2021 |
| Efficient derivation and genetic modifications of human pluripotent stem cells on engineered human feeder cell lines C Zou, BK Chou, SN Dowey, K Tsang, X Huang, CF Liu, C Smith, J Yen, ... Stem cells and development 21 (12), 2298-2311, 2012 | 36 | 2012 |
| Cationic, helical polypeptide-based gene delivery for IMR-90 fibroblasts and human embryonic stem cells J Yen, Y Zhang, NP Gabrielson, L Yin, L Guan, I Chaudhury, H Lu, ... Biomaterials science 1 (7), 719-727, 2013 | 35 | 2013 |
| Redox-responsive self-assembled chain-shattering polymeric therapeutics K Cai, J Yen, Q Yin, Y Liu, Z Song, S Lezmi, Y Zhang, X Yang, ... Biomaterials science 3 (7), 1061-1065, 2015 | 30 | 2015 |
| Bioorthogonal oxime ligation mediated in vivo cancer targeting L Tang, Q Yin, Y Xu, Q Zhou, K Cai, J Yen, LW Dobrucki, J Cheng Chemical science 6 (4), 2182-2186, 2015 | 30 | 2015 |
| CD44 Mediated nonviral gene delivery into human embryonic stem cells via hyaluronic-acid-coated nanoparticles J Yen, H Ying, H Wang, L Yin, F Uckun, J Cheng ACS Biomaterials Science & Engineering 2 (3), 326-335, 2016 | 27 | 2016 |
| An improved method for generating and identifying human induced pluripotent stem cells P Mali, Z Ye, BK Chou, J Yen, L Cheng Methods Mol Biol 636, 191-205, 2010 | 25 | 2010 |
| TRIAMF: a new method for delivery of Cas9 ribonucleoprotein complex to human hematopoietic stem cells J Yen, M Fiorino, Y Liu, S Paula, S Clarkson, L Quinn, WR Tschantz, ... Scientific reports 8 (1), 1-11, 2018 | 22 | 2018 |
| Degradable and biocompatible hydrogels bearing a hindered urea bond H Ying, J Yen, R Wang, Y Lai, Y Hu, J Cheng Biomaterials science 5 (12), 2398-2402, 2017 | 14 | 2017 |
| Enhanced non-viral gene delivery to human embryonic stem cells via small molecule-mediated transient alteration of the cell structure J Yen, L Yin, J Cheng Journal of Materials Chemistry B 2 (46), 8098-8105, 2014 | 14 | 2014 |
| Complementary base editing approaches for the treatment of sickle cell disease and beta thalassemia L Lin, AP Rybak, C Rinaldi, J Yen, Y Fu, E Akrawi, S Smith, SJ Haskett, ... Blood 134, 3352, 2019 | 6 | 2019 |
| Base Editing Eliminates the Sickle Cell Mutation and Pathology in Hematopoietic Stem Cells Derived Erythroid Cells JS Yen, GA Newby, T Mayuranathan, SN Porter, Y Yao, KJ Woodard, ... Blood 136, 13-14, 2020 | 3 | 2020 |
| Adenosine base editing of γ-globin promoters induces fetal hemoglobin and inhibit erythroid sickling T Mayuranathan, JS Yen, GA Newby, Y Yao, SN Porter, KJ Woodard, ... Blood 136, 21-22, 2020 | 3 | 2020 |
| Base Editing for SCD J Yen 63rd ASH Annual Meeting and Exposition, 2021 | | 2021 |
