A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2α S Seidel, BK Garvalov, V Wirta, L Von Stechow, A Schänzer, K Meletis, ... Brain 133 (4), 983-995, 2010 | 545 | 2010 |
p53 suppresses the self-renewal of adult neural stem cells K Meletis, V Wirta, SM Hede, M Nistér, J Lundeberg, J Frisén Oxford University Press for The Company of Biologists Limited 133 (2), 363-369, 2006 | 494 | 2006 |
Versatile gene-specific sequence tags for Arabidopsis functional genomics: transcript profiling and reverse genetics applications P Hilson, J Allemeersch, T Altmann, S Aubourg, A Avon, J Beynon, ... Genome research 14 (10b), 2176-2189, 2004 | 383 | 2004 |
Integration of whole genome sequencing into a healthcare setting: high diagnostic rates across multiple clinical entities in 3219 rare disease patients H Stranneheim, K Lagerstedt-Robinson, M Magnusson, M Kvarnung, ... Genome Medicine 13, 1-15, 2021 | 151 | 2021 |
Sarek: A portable workflow for whole-genome sequencing analysis of germline and somatic variants M Garcia, S Juhos, M Larsson, PI Olason, M Martin, J Eisfeldt, ... F1000Research 9, 2020 | 129 | 2020 |
From cytogenetics to cytogenomics: whole-genome sequencing as a first-line test comprehensively captures the diverse spectrum of disease-causing genetic variation underlying … A Lindstrand, J Eisfeldt, M Pettersson, CMB Carvalho, M Kvarnung, ... Genome medicine 11, 1-23, 2019 | 109 | 2019 |
Genome wide gene amplifications and deletions in Plasmodium falciparum U Ribacke, BW Mok, V Wirta, J Normark, J Lundeberg, F Kironde, ... Molecular and biochemical parasitology 155 (1), 33-44, 2007 | 108 | 2007 |
Rapid pulsed whole genome sequencing for comprehensive acute diagnostics of inborn errors of metabolism H Stranneheim, M Engvall, K Naess, N Lesko, P Larsson, M Dahlberg, ... BMC genomics 15, 1-10, 2014 | 77 | 2014 |
Lab-on-DVD: standard DVD drives as a novel laser scanning microscope for image based point of care diagnostics H Ramachandraiah, M Amasia, J Cole, P Sheard, S Pickhaver, C Walker, ... Lab on a Chip 13 (8), 1578-1585, 2013 | 71 | 2013 |
Whole‐genome sequencing of cytogenetically balanced chromosome translocations identifies potentially pathological gene disruptions and highlights the importance of … D Nilsson, M Pettersson, P Gustavsson, A Förster, W Hofmeister, ... Human mutation 38 (2), 180-192, 2017 | 66 | 2017 |
CTNND2—a candidate gene for reading problems and mild intellectual disability W Hofmeister, D Nilsson, A Topa, BM Anderlid, F Darki, H Matsson, ... Journal of medical genetics 52 (2), 111-122, 2015 | 48 | 2015 |
Replicative and non-replicative mechanisms in the formation of clustered CNVs are indicated by whole genome characterization L Nazaryan-Petersen, J Eisfeldt, M Pettersson, J Lundin, D Nilsson, ... PLoS genetics 14 (11), e1007780, 2018 | 33 | 2018 |
Trailblazing precision medicine in Europe: A joint view by Genomic Medicine Sweden and the Centers for Personalized Medicine, ZPM, in Germany A Stenzinger, A Edsjö, C Ploeger, M Friedman, S Fröhling, V Wirta, ... Seminars in Cancer Biology 84, 242-254, 2022 | 27 | 2022 |
High diagnostic yield in skeletal ciliopathies using massively parallel genome sequencing, structural variant screening and RNA analyses A Hammarsjö, M Pettersson, D Chitayat, A Handa, BM Anderlid, ... Journal of Human Genetics 66 (10), 995-1008, 2021 | 26 | 2021 |
Bioinformatory‐assisted analysis of next‐generation sequencing data for precision medicine in pancreatic cancer L Malgerud, J Lindberg, V Wirta, M Gustafsson‐Liljefors, M Karimi, ... Molecular Oncology 11 (10), 1413-1429, 2017 | 26 | 2017 |
Performance of a 70-mer oligonucleotide microarray for genotyping of Campylobacter jejuni S Rodin, AF Andersson, V Wirta, L Eriksson, M Ljungström, B Björkholm, ... BMC microbiology 8, 1-10, 2008 | 26 | 2008 |
Global gene expression analyses of hematopoietic stem cell-like cell lines with inducible Lhx2 expression K Richter, V Wirta, L Dahl, S Bruce, J Lundeberg, L Carlsson, C Williams BMC genomics 7, 1-19, 2006 | 23 | 2006 |
Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions B Gong, D Li, R Kusko, N Novoradovskaya, Y Zhang, S Wang, ... Genome biology 22, 1-23, 2021 | 21 | 2021 |
Implementing precision medicine in a regionally organized healthcare system in Sweden T Fioretos, V Wirta, L Cavelier, E Berglund, M Friedman, M Akhras, ... Nature Medicine 28 (10), 1980-1982, 2022 | 20 | 2022 |
Novel candidate genes for atherosclerosis are identified by representational difference analysis-based transcript profiling of cholesterol-loaded macrophages T Andersson, S Boräng, M Larsson, V Wirta, A Wennborg, J Lundeberg, ... Pathobiology 69 (6), 304-314, 2002 | 19 | 2002 |