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Luke Arbogast
Luke Arbogast
Eli Lilly and Company
Verified email at ibbr.umd.edu
Title
Cited by
Cited by
Year
Mapping Monoclonal Antibody Structure by 2D 13C NMR at Natural Abundance
LW Arbogast, RG Brinson, JP Marino
Analytical Chemistry, 2015
1332015
Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics
RG Brinson, JP Marino, F Delaglio, LW Arbogast, RM Evans, A Kearsley, ...
MAbs 11 (1), 94-105, 2019
76*2019
Multivariate Analysis of Two-Dimensional 1H, 13C Methyl NMR Spectra of Monoclonal Antibody Therapeutics To Facilitate Assessment of Higher Order Structure
LW Arbogast, F Delaglio, JE Schiel, JP Marino
Analytical chemistry 89 (21), 11839-11845, 2017
752017
Non-Uniform Sampling for All: More NMR Spectral Quality, Less Measurement Time
F Delaglio, GS Walker, K Farley, R Sharma, J Hoch, L Arbogast, ...
American Pharmaceutical Review 20 (4), 56-60, 2017
682017
2D 1HN, 15N Correlated NMR Methods at Natural Abundance for Obtaining Structural Maps and Statistical Comparability of Monoclonal Antibodies
LW Arbogast, RG Brinson, T Formolo, JT Hoopes, JP Marino
Pharmaceutical research 33, 462-475, 2016
562016
Application of Natural Isotopic Abundance 1H–13C- and 1H–15N-Correlated Two-Dimensional NMR for Evaluation of the Structure of Protein Therapeutics
LW Arbogast, RG Brinson, JP Marino
Methods In Enzymology, 2015
422015
Emerging Technologies To Assess the Higher Order Structure of Monoclonal Antibodies
JP Marino, RG Brinson, JW Hudgens, JE Ladner, DT Gallagher, ...
State-of-the-Art and Emerging Technologies for Therapeutic Monoclonal …, 2015
27*2015
Selective suppression of excipient signals in 2D 1H–13C methyl spectra of biopharmaceutical products
LW Arbogast, F Delaglio, JR Tolman, JP Marino
Journal of biomolecular NMR 72, 149-161, 2018
212018
Best practices in utilization of 2D-NMR spectral data as the input for chemometric analysis in biopharmaceutical applications
RG Brinson, LW Arbogast, JP Marino, F Delaglio
Journal of Chemical Information and Modeling 60 (4), 2339-2355, 2020
172020
Principal component analysis for automated classification of 2D spectra and interferograms of protein therapeutics: influence of noise, reconstruction details, and data preparation
RG Brinson, KW Elliott, LW Arbogast, DA Sheen, JP Giddens, JP Marino, ...
Journal of Biomolecular NMR 74, 643-656, 2020
132020
Comparative Analysis of One-Dimensional Protein Fingerprint by Line Shape Enhancement and Two-Dimensional 1H,13C Methyl NMR Methods for …
KW Elliott, H Ghasriani, M Wikström, JP Giddens, Y Aubin, F Delaglio, ...
Analytical chemistry 92 (9), 6366-6373, 2020
132020
HNCO-based measurement of one-bond amide 15N-1H couplings with optimized precision
L Arbogast, A Majumdar, JR Tolman
Journal of biomolecular NMR 46, 175-189, 2010
132010
Principal component analysis of 1D 1H diffusion edited NMR spectra of protein therapeutics
KW Elliott, F Delaglio, M Wikström, JP Marino, LW Arbogast
Journal of pharmaceutical sciences 110 (10), 3385-3394, 2021
102021
Assessment of the Higher‐Order Structure of Formulated Monoclonal Antibody Therapeutics by 2D Methyl Correlated NMR and Principal Component Analysis
LW Arbogast, F Delaglio, RG Brinson, JP Marino
Current protocols in protein science 100 (1), e105, 2020
92020
Interlaboratory studies using the NISTmAb to advance biopharmaceutical structural analytics
K Yandrofski, T Mouchahoir, ML De Leoz, D Duewer, JW Hudgens, ...
Frontiers in Molecular Biosciences 9, 876780, 2022
82022
Chemometric outlier classification of 2D-NMR spectra to enable higher order structure characterization of protein therapeutics
DA Sheen, VK Shen, RG Brinson, LW Arbogast, JP Marino, F Delaglio
Chemometrics and Intelligent Laboratory Systems 199, 103973, 2020
62020
Heterologous recombinant expression of non-originator NISTmAb
L Kashi, K Yandrofski, RJ Preston, LW Arbogast, JP Giddens, JP Marino, ...
MAbs 10 (6), 922-933, 2018
42018
Unraveling long range residual dipolar coupling networks in strongly aligned proteins
L Arbogast, A Majumdar, JR Tolman
Journal of Magnetic Resonance 235, 26-31, 2013
42013
Selective spin inversion in solution by magic field cross polarization
JR Tolman, LW Arbogast
Journal of Magnetic Resoance, 2019
32019
Solid-state NMR characterization of lyophilized formulations of monoclonal antibody therapeutics
J Perodeau, LW Arbogast, AJ Nieuwkoop
Molecular pharmaceutics 20 (3), 1480-1489, 2023
12023
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