Amiodarone Has Intrinsic Anti-Trypanosoma cruzi Activity and Acts Synergistically with Posaconazole G Benaim, JM Sanders, Y Garcia-Marchán, C Colina, R Lira, AR Caldera, ... Journal of medicinal chemistry 49 (3), 892-899, 2006 | 247 | 2006 |
Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region ME Grillet, JV Hernández-Villena, MS Llewellyn, AE Paniz-Mondolfi, ... The Lancet Infectious Diseases 19 (5), e149-e161, 2019 | 211 | 2019 |
Phosphorylation of calmodulin: functional implications G Benaim, A Villalobo European Journal of Biochemistry 269 (15), 3619-3631, 2002 | 203 | 2002 |
Different conformational states of the purified Ca2+-ATPase of the erythrocyte plasma membrane revealed by controlled trypsin proteolysis. G Benaim, M Zurini, E Carafoli Journal of Biological Chemistry 259 (13), 8471-8477, 1984 | 121 | 1984 |
Amiodarone Destabilizes Intracellular Ca2+ Homeostasis and Biosynthesis of Sterols in Leishmania mexicana X Serrano-Martín, Y García-Marchan, A Fernandez, N Rodriguez, H Rojas, ... Antimicrobial Agents and Chemotherapy 53 (4), 1403-1410, 2009 | 101 | 2009 |
Mechanism of action of miltefosine on Leishmania donovani involves the impairment of acidocalcisome function and the activation of the sphingosine-dependent plasma membrane … AK Pinto-Martinez, J Rodriguez-Durán, X Serrano-Martin, ... Antimicrobial agents and chemotherapy 62 (1), 10.1128/aac. 01614-17, 2018 | 95 | 2018 |
Na+ entry via glutamate transporter activates the reverse Na+/Ca2+ exchange and triggers ‐induced Ca2+ release in rat cerebellar Type‐1 astrocytes H Rojas, C Colina, M Ramos, G Benaim, EH Jaffe, C Caputo, R DiPolo Journal of neurochemistry 100 (5), 1188-1202, 2007 | 95 | 2007 |
Amiodarone and Miltefosine Act Synergistically against Leishmania mexicana and Can Induce Parasitological Cure in a Murine Model of Cutaneous Leishmaniasis X Serrano-Martín, G Payares, M De Lucca, JC Martinez, A Mendoza-León, ... Antimicrobial Agents and Chemotherapy 53 (12), 5108-5113, 2009 | 88 | 2009 |
Targeting calcium homeostasis as the therapy of Chagas’ disease and leishmaniasis–a review G Benaim, C Garcia Tropical Biomedicine, 2011 | 87 | 2011 |
A calmodulin-activated (Ca2+-Mg2+)-ATPase is involved in Ca2+ transport by plasma membrane vesicles from Trypanosoma cruzi G Benaim, S Losada, FR Gadelha, R Docampo Biochemical Journal 280 (3), 715-720, 1991 | 86 | 1991 |
Ca2+ transport in isolated mitochondrial vesicles from Leishmania braziliensis promastigotes G Benaim, R Bermudez, JA Urbina Molecular and biochemical parasitology 39 (1), 61-68, 1990 | 84 | 1990 |
A calmodulin-stimulated Ca2+ pump in plasma-membrane vesicles from Trypanosoma brucei; selective inhibition by pentamidine G Benaim, C Lopez-Estrano, R Docampo, SNJ Moreno Biochemical Journal 296 (3), 759-763, 1993 | 77 | 1993 |
The emerging role of amiodarone and dronedarone in Chagas disease G Benaim, AE Paniz Mondolfi Nature Reviews Cardiology 9 (10), 605-609, 2012 | 76 | 2012 |
SQ109, a new drug lead for Chagas disease P Veiga-Santos, K Li, L Lameira, TMU De Carvalho, G Huang, M Galizzi, ... Antimicrobial agents and chemotherapy 59 (4), 1950-1961, 2015 | 74 | 2015 |
A calcium pump in plasma membrane vesicles from Leishmania braziliensis G Benaim, PJ Romero Biochimica et Biophysica Acta (BBA)-Biomembranes 1027 (1), 79-84, 1990 | 65 | 1990 |
In Vitro Anti-Trypanosoma cruzi Activity of Dronedarone, a Novel Amiodarone Derivative with an Improved Safety Profile G Benaim, V Hernandez-Rodriguez, S Mujica-Gonzalez, L Plaza-Rojas, ... Antimicrobial agents and chemotherapy 56 (7), 3720-3725, 2012 | 63 | 2012 |
The marine sponge toxin agelasine B increases the intracellular Ca2+ concentration and induces apoptosis in human breast cancer cells (MCF-7) AA Pimentel, P Felibertt, F Sojo, L Colman, A Mayora, ML Silva, H Rojas, ... Cancer chemotherapy and pharmacology 69, 71-83, 2012 | 61 | 2012 |
Successful Treatment of Old World Cutaneous Leishmaniasis Caused by Leishmania infantum with Posaconazole AE Paniz Mondolfi, C Stavropoulos, T Gelanew, E Loucas, ... Antimicrobial Agents and Chemotherapy 55 (4), 1774-1776, 2011 | 60 | 2011 |
Ceramide-1-P induces Ca2+ mobilization in Jurkat T-cells by elevation of Ins (1, 4, 5)-P3 and activation of a store-operated calcium channel C Colina, A Flores, C Castillo, M del Rosario Garrido, A Israel, R DiPolo, ... Biochemical and biophysical research communications 336 (1), 54-60, 2005 | 55 | 2005 |
Disruption of Intracellular Calcium Homeostasis as a Therapeutic Target Against Trypanosoma cruzi G Benaim, AE Paniz-Mondolfi, EM Sordillo, N Martinez-Sotillo Frontiers in cellular and infection microbiology 10, 46, 2020 | 54 | 2020 |