| Identification of predictive biomarkers for cytokine release syndrome after chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia DT Teachey, SF Lacey, PA Shaw, JJ Melenhorst, SL Maude, N Frey, ... Cancer discovery 6 (6), 664-679, 2016 | 986 | 2016 |
| A novel doxycycline‐inducible system for the transgenic analysis of mammary gland biology EJ Gunther, GK Belka, GBW Wertheim, J Wang, JL Hartman, RB Boxer, ... The FASEB Journal 16 (3), 283-292, 2002 | 262 | 2002 |
| Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy VG Bhoj, D Arhontoulis, G Wertheim, J Capobianchi, CA Callahan, ... Blood, The Journal of the American Society of Hematology 128 (3), 360-370, 2016 | 225 | 2016 |
| CAR T-cell therapy is effective for CD19-dim B-lymphoblastic leukemia but is impacted by prior blinatumomab therapy V Pillai, K Muralidharan, W Meng, A Bagashev, DA Oldridge, J Rosenthal, ... Blood advances 3 (22), 3539-3549, 2019 | 164 | 2019 |
| Risk-adapted preemptive tocilizumab to prevent severe cytokine release syndrome after CTL019 for pediatric B-cell acute lymphoblastic leukemia: a prospective clinical trial S Kadauke, RM Myers, Y Li, R Aplenc, D Baniewicz, DM Barrett, ... Journal of Clinical Oncology 39 (8), 920-930, 2021 | 136 | 2021 |
| Humanized CD19-targeted chimeric antigen receptor (CAR) T cells in CAR-naive and CAR-exposed children and young adults with relapsed or refractory acute lymphoblastic leukemia RM Myers, Y Li, A Barz Leahy, DM Barrett, DT Teachey, C Callahan, ... Journal of Clinical Oncology 39 (27), 3044-3055, 2021 | 108 | 2021 |
| Repeated loss of target surface antigen after immunotherapy in primary mediastinal large B cell lymphoma H Yu, E Sotillo, C Harrington, G Wertheim, M Paessler, SL Maude, ... American journal of hematology 92 (1), E11, 2017 | 103 | 2017 |
| Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6 blockade–refractory idiopathic multicentric Castleman disease DC Fajgenbaum, RA Langan, AS Japp, HL Partridge, SK Pierson, ... The Journal of clinical investigation 129 (10), 4451-4463, 2019 | 101 | 2019 |
| A PERK–miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival Y Bu, A Yoshida, N Chitnis, BJ Altman, F Tameire, A Oran, V Gennaro, ... Nature cell biology 20 (1), 104-115, 2018 | 99 | 2018 |
| High incidence of Philadelphia chromosome-like acute lymphoblastic leukemia in older adults with B-ALL SK Tasian, C Hurtz, GB Wertheim, NG Bailey, MS Lim, RC Harvey, ... Leukemia 31 (4), 981-984, 2017 | 95 | 2017 |
| The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells DM Gerhardt, KV Pajcini, T D’altri, LL Tu, R Jain, L Xu, MJ Chen, ... Genes & development 28 (6), 576-593, 2014 | 73 | 2014 |
| Increased mTOR activation in idiopathic multicentric Castleman disease DJ Arenas, K Floess, D Kobrin, RAL Pai, MB Srkalovic, MA Tamakloe, ... Blood, The Journal of the American Society of Hematology 135 (19), 1673-1684, 2020 | 61 | 2020 |
| Clinical efficacy of ruxolitinib and chemotherapy in a child with Philadelphia chromosome-like acute lymphoblastic leukemia with GOLGA5-JAK2 fusion and induction failure YY Ding, JW Stern, TF Jubelirer, GB Wertheim, F Lin, F Chang, Z Gu, ... Haematologica 103 (9), e427, 2018 | 58 | 2018 |
| Ikaros imposes a barrier to CD8+ T cell differentiation by restricting autocrine IL-2 production S O’Brien, RM Thomas, GB Wertheim, F Zhang, H Shen, AD Wells The Journal of Immunology 192 (11), 5118-5129, 2014 | 57 | 2014 |
| NTRK fusions identified in pediatric tumors: the frequency, fusion partners, and clinical outcome X Zhao, C Kotch, E Fox, LF Surrey, GB Wertheim, ZW Baloch, F Lin, ... JCO precision oncology 1, 204-214, 2021 | 55 | 2021 |
| Cytosine deaminase APOBEC3A sensitizes leukemia cells to inhibition of the DNA replication checkpoint AM Green, K Budagyan, KE Hayer, MA Reed, MR Savani, GB Wertheim, ... Cancer research 77 (17), 4579-4588, 2017 | 55 | 2017 |
| Heterogeneity of surface CD19 and CD22 expression in B lymphoblastic leukemia J Rosenthal, AS Naqvi, M Luo, G Wertheim, M Paessler, ... American Journal of Hematology 93 (11), E352-E355, 2018 | 50 | 2018 |
| Cloning and Characterization of Hunk, a Novel Mammalian SNF1-Related Protein Kinase HP Gardner, GBW Wertheim, SI Ha, NG Copeland, DJ Gilbert, NA Jenkins, ... Genomics 63 (1), 46-59, 2000 | 50 | 2000 |
| Developmental role of the SNF1-related kinase Hunk in pregnancy-induced changes in the mammary gland HP Gardner, GK Belka, GBW Wertheim, JL Hartman, SI Ha, PA Gimotty, ... Development 127 (20), 4493-4509, 2000 | 48 | 2000 |
| Runx1 negatively regulates inflammatory cytokine production by neutrophils in response to Toll-like receptor signaling DC Bellissimo, C Chen, Q Zhu, S Bagga, CT Lee, B He, GB Wertheim, ... Blood advances 4 (6), 1145-1158, 2020 | 46 | 2020 |
