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Ajay Kumar
Ajay Kumar
Principal Scientist, CSIR-IIIM, Jammu, India
Verified email at iiim.res.in - Homepage
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Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
106902021
Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound withaferin A with …
F Malik, A Kumar, S Bhushan, S Khan, A Bhatia, KA Suri, GN Qazi, ...
Apoptosis 12, 2115-2133, 2007
2882007
An essential oil and its major constituent isointermedeol induce apoptosis by increased expression of mitochondrial cytochrome c and apical death receptors in human leukaemia …
A Kumar, F Malik, S Bhushan, VK Sethi, AK Shahi, SC Taneja, GN Qazi, ...
Chemico-biological interactions 171 (3), 332-347, 2008
1552008
A triterpenediol from Boswellia serrata induces apoptosis through both the intrinsic and extrinsic apoptotic pathways in human leukemia HL-60 cells
S Bhushan, A Kumar, F Malik, SS Andotra, VK Sethi, IP Kaur, SC Taneja, ...
Apoptosis 12, 1911-1926, 2007
1452007
Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway
A Wani, M Gupta, M Ahmad, AM Shah, AU Ahsan, PH Qazi, F Malik, ...
Autophagy 15 (10), 1810-1828, 2019
902019
Crocus sativus Extract Tightens the Blood-Brain Barrier, Reduces Amyloid β Load and Related Toxicity in 5XFAD Mice
YS Batarseh, SS Bharate, V Kumar, A Kumar, RA Vishwakarma, ...
ACS chemical neuroscience 8 (8), 1756-1766, 2017
792017
Autophagy triggered by magnolol derivative negatively regulates angiogenesis
S Kumar, SK Guru, AS Pathania, A Kumar, S Bhushan, F Malik
Cell death & disease 4 (10), e889-e889, 2013
792013
Secalonic acid-D represses HIF1α/VEGF-mediated angiogenesis by regulating the Akt/mTOR/p70S6K signaling cascade
SK Guru, AS Pathania, S Kumar, D Ramesh, M Kumar, S Rana, A Kumar, ...
Cancer research 75 (14), 2886-2896, 2015
782015
Immune modulation and apoptosis induction: Two sides of antitumoural activity of a standardised herbal formulation of Withania somnifera
F Malik, A Kumar, S Bhushan, DM Mondhe, HC Pal, R Sharma, A Khajuria, ...
European Journal of Cancer 45 (8), 1494-1509, 2009
782009
Discovery of a marine-derived bis-indole alkaloid fascaplysin, as a new class of potent P-glycoprotein inducer and establishment of its structure–activity relationship
S Manda, S Sharma, A Wani, P Joshi, V Kumar, SK Guru, SS Bharate, ...
European journal of medicinal chemistry 107, 1-11, 2016
762016
Crocetin promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway
A Wani, SB Al Rihani, A Sharma, B Weadick, R Govindarajan, SU Khan, ...
Autophagy 17 (11), 3813-3832, 2021
722021
Boeravinone B, A Novel Dual Inhibitor of NorA Bacterial Efflux Pump of Staphylococcus aureus and Human P-Glycoprotein, Reduces the Biofilm Formation and …
S Singh, NP Kalia, P Joshi, A Kumar, PR Sharma, A Kumar, SB Bharate, ...
Frontiers in microbiology 8, 1868, 2017
722017
Cytotoxic and apoptotic activities of novel amino analogues of boswellic acids
BA Shah, A Kumar, P Gupta, M Sharma, VK Sethi, AK Saxena, J Singh, ...
Bioorganic & medicinal chemistry letters 17 (23), 6411-6416, 2007
722007
Enhanced Anticancer Potential of Encapsulated Solid Lipid Nanoparticles of TPD: A Novel Triterpenediol from Boswellia serrata
S Bhushan, V Kakkar, HC Pal, SK Guru, A Kumar, DM Mondhe, ...
Molecular pharmaceutics 10 (1), 225-235, 2013
612013
Fascaplysin induces caspase mediated crosstalk between apoptosis and autophagy through the inhibition of PI3K/AKT/mTOR signaling cascade in human leukemia HL‐60 cells
S Kumar, SK Guru, AS Pathania, S Manda, A Kumar, SB Bharate, ...
Journal of Cellular Biochemistry 116 (6), 985-997, 2015
602015
Activation of p53/p21/PUMA alliance and disruption of PI‐3/Akt in multimodal targeting of apoptotic signaling cascades in cervical cancer cells by a pentacyclic triterpenediol …
S Bhushan, F Malik, A Kumar, HK Isher, IP Kaur, SC Taneja, J Singh
Molecular Carcinogenesis: Published in cooperation with the University of …, 2009
572009
Osthol and curcumin as inhibitors of human Pgp and multidrug efflux pumps of Staphylococcus aureus: reversing the resistance against frontline antibacterial drugs
P Joshi, S Singh, A Wani, S Sharma, SK Jain, B Singh, BD Gupta, NK Satti, ...
MedChemComm 5 (10), 1540-1547, 2014
552014
Discovery of Quinazolin-4(3H)-ones as NLRP3 Inflammasome Inhibitors: Computational Design, Metal-Free Synthesis, and in Vitro Biological Evaluation
M Abdullaha, S Mohammed, M Ali, A Kumar, RA Vishwakarma, ...
The Journal of Organic Chemistry 84 (9), 5129-5140, 2019
512019
Acyl derivatives of boswellic acids as inhibitors of NF-κB and STATs
A Kumar, BA Shah, S Singh, A Hamid, SK Singh, VK Sethi, AK Saxena, ...
Bioorganic & medicinal chemistry letters 22 (1), 431-435, 2012
512012
Identification of embelin, a 3‐undecyl‐1,4‐benzoquinone from Embelia ribes as a multitargeted anti‐Alzheimer agent
VK Nuthakki, A Sharma, A Kumar, SB Bharate
Drug Development Research 80 (5), 655-665, 2019
452019
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