| Pharmacological modulation of chemokine receptor function DJ Scholten, M Canals, D Maussang, L Roumen, MJ Smit, M Wijtmans, ... British journal of pharmacology 165 (6), 1617-1643, 2012 | 296 | 2012 |
| Keynote review: histamine H3 receptor antagonists reach out for the clinic S Celanire, M Wijtmans, P Talaga, R Leurs, IJP De Esch Drug discovery today 10 (23-24), 1613-1627, 2005 | 261 | 2005 |
| Chemical insights in the concept of hybrid drugs: the antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin N Hulsman, JP Medema, C Bos, A Jongejan, R Leurs, MJ Smit, ... Journal of medicinal chemistry 50 (10), 2424-2431, 2007 | 180 | 2007 |
| 6-Amino-3-pyridinols: towards diffusion-controlled chain-breaking antioxidants M Wijtmans, DA Pratt, L Valgimigli, GA DiLabio, GF Pedulli, NA Porter Angewandte Chemie International Edition 42 (36), 4370-4373, 2003 | 180 | 2003 |
| Development of a selective ESI-MS derivatization reagent: synthesis and optimization for the analysis of aldehydes in biological mixtures M Eggink, M Wijtmans, R Ekkebus, H Lingeman, IJP Esch, J Kool, ... Analytical chemistry 80 (23), 9042-9051, 2008 | 125 | 2008 |
| Synthesis and reactivity of some 6-substituted-2, 4-dimethyl-3-pyridinols, a novel class of chain-breaking antioxidants M Wijtmans, DA Pratt, J Brinkhorst, R Serwa, L Valgimigli, GF Pedulli, ... The Journal of Organic Chemistry 69 (26), 9215-9223, 2004 | 117 | 2004 |
| Histamine H3 receptor ligands break ground in a remarkable plethora of therapeutic areas M Wijtmans, R Leurs, I Esch Expert opinion on investigational drugs 16 (7), 967-985, 2007 | 111 | 2007 |
| En route to new blockbuster anti-histamines: surveying the offspring of the expanding histamine receptor family R Leurs, HF Vischer, M Wijtmans, IJP de Esch Trends in pharmacological sciences 32 (4), 250-257, 2011 | 101 | 2011 |
| Towards small‐molecule CXCR3 ligands with clinical potential M Wijtmans, D Verzijl, R Leurs, IJP de Esch, MJ Smit ChemMedChem: Chemistry Enabling Drug Discovery 3 (6), 861-872, 2008 | 90 | 2008 |
| Targeted LC–MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBA M Eggink, M Wijtmans, A Kretschmer, J Kool, H Lingeman, IJP de Esch, ... Analytical and bioanalytical chemistry 397, 665-675, 2010 | 88 | 2010 |
| Virtual Fragment Screening: Discovery of Histamine H3 Receptor Ligands Using Ligand-Based and Protein-Based Molecular Fingerprints F Sirci, EP Istyastono, HF Vischer, AJ Kooistra, S Nijmeijer, M Kuijer, ... Journal of chemical information and modeling 52 (12), 3308-3324, 2012 | 85 | 2012 |
| Pharmacological characterization of a small‐molecule agonist for the chemokine receptor CXCR3 DJ Scholten, M Canals, M Wijtmans, S de Munnik, P Nguyen, D Verzijl, ... British journal of pharmacology 166 (3), 898-911, 2012 | 67 | 2012 |
| Several down, a few to go: histamine H3 receptor ligands making the final push towards the market? S Kuhne, M Wijtmans, HD Lim, R Leurs, IJP de Esch Expert opinion on investigational drugs 20 (12), 1629-1648, 2011 | 67 | 2011 |
| Activating students’ interest and participation in lectures and practical courses using their electronic devices M Wijtmans, L Van Rens, JE van Muijlwijk-Koezen Journal of chemical education 91 (11), 1830-1837, 2014 | 66 | 2014 |
| Synthesis, modeling and functional activity of substituted styrene-amides as small-molecule CXCR7 agonists M Wijtmans, D Maussang, F Sirci, DJ Scholten, M Canals, A Mujić-Delić, ... European journal of medicinal chemistry 51, 184-192, 2012 | 66 | 2012 |
| Synthesis and characterization of a bidirectional photoswitchable antagonist toolbox for real-time GPCR photopharmacology NJ Hauwert, TAM Mocking, D Da Costa Pereira, AJ Kooistra, LM Wijnen, ... Journal of the American Chemical Society 140 (12), 4232-4243, 2018 | 63 | 2018 |
| Derivatization of the tricarboxylic acid cycle intermediates and analysis by online solid-phase extraction-liquid chromatography–mass spectrometry with positive-ion … D Kloos, RJE Derks, M Wijtmans, H Lingeman, OA Mayboroda, ... Journal of Chromatography A 1232, 19-26, 2012 | 60 | 2012 |
| 4, 6-Diphenylpyridines as promising novel anti-influenza agents targeting the PA–PB1 protein–protein interaction: Structure–activity relationships exploration with the aid of … IML Trist, G Nannetti, C Tintori, AL Fallacara, D Deodato, B Mercorelli, ... Journal of Medicinal Chemistry 59 (6), 2688-2703, 2016 | 58 | 2016 |
| Visible light excitation of CdSe nanocrystals triggers the release of coumarin from cinnamate surface ligands M Wijtmans, SJ Rosenthal, B Zwanenburg, NA Porter Journal of the American Chemical Society 128 (35), 11720-11726, 2006 | 55 | 2006 |
| Modulators of CXCR4 and CXCR7/ACKR3 function I Adlere, B Caspar, M Arimont, S Dekkers, K Visser, J Stuijt, C de Graaf, ... Molecular pharmacology 96 (6), 737-752, 2019 | 54 | 2019 |
