| Novel HIV-1 integrase inhibitors derived from quinolone antibiotics M Sato, T Motomura, H Aramaki, T Matsuda, M Yamashita, Y Ito, ... Journal of medicinal chemistry 49 (5), 1506-1508, 2006 | 463 | 2006 |
| Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir (JTK-303/GS-9137) K Shimura, E Kodama, Y Sakagami, Y Matsuzaki, W Watanabe, ... Journal of virology 82 (2), 764-774, 2008 | 436 | 2008 |
| Remodeling of gp41‐C34 peptide leads to highly effective inhibitors of the fusion of HIV‐1 with target cells A Otaka, M Nakamura, D Nameki, E Kodama, S Uchiyama, S Nakamura, ... Angewandte Chemie 114 (16), 3061-3064, 2002 | 209 | 2002 |
| Antileukemic activity and mechanism of action of cordycepin against terminal deoxynucleotidyl transferase-positive (TdT+) leukemic cells EN Kodama, RP McCaffrey, K Yusa, H Mitsuya Biochemical pharmacology 59 (3), 273-281, 2000 | 198 | 2000 |
| 4′-Ethynyl nucleoside analogs: potent inhibitors of multidrug-resistant human immunodeficiency virus variants in vitro EI Kodama, S Kohgo, K Kitano, H Machida, H Gatanaga, S Shigeta, ... Antimicrobial agents and chemotherapy 45 (5), 1539-1546, 2001 | 185 | 2001 |
| Development of specific CXCR4 inhibitors possessing high selectivity indexes as well as complete stability in serum based on an anti-HIV peptide T140 H Tamamura, A Omagari, K Hiramatsu, K Gotoh, T Kanamoto, Y Xu, ... Bioorganic & medicinal chemistry letters 11 (14), 1897-1902, 2001 | 158 | 2001 |
| Broad spectrum anti-RNA virus activities of titanium and vanadium substituted polyoxotungstates S Shigeta, S Mori, E Kodama, J Kodama, K Takahashi, T Yamase Antiviral research 58 (3), 265-271, 2003 | 154 | 2003 |
| Broad Spectrum Anti-RNA Virus Activities of Titanium or Vanadium Substituted Polyoxotangstates.: 148 S Shigeta, S Mori, E Kodama, T Yamase Antiviral Research 57 (3), 2003 | 154* | 2003 |
| Mechanism of inhibition of HIV-1 reverse transcriptase by 4′-ethynyl-2-fluoro-2′-deoxyadenosine triphosphate, a translocation-defective reverse transcriptase inhibitor E Michailidis, B Marchand, EN Kodama, K Singh, M Matsuoka, KA Kirby, ... Journal of Biological Chemistry 284 (51), 35681-35691, 2009 | 153 | 2009 |
| A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication S Hattori, N Higashi-Kuwata, H Hayashi, SR Allu, J Raghavaiah, H Bulut, ... Nature communications 12 (1), 1-12, 2021 | 149 | 2021 |
| Epigallocatechin gallate inhibits the HIV reverse transcription step S Li, T Hattori, EN Kodama Antiviral Chemistry and Chemotherapy 21 (6), 239-243, 2011 | 127 | 2011 |
| Cohort profile: tohoku medical megabank project birth and three-generation cohort study (tmm birthree cohort study): rationale, progress and perspective S Kuriyama, H Metoki, M Kikuya, T Obara, M Ishikuro, C Yamanaka, ... International journal of epidemiology 49 (1), 18-19m, 2020 | 125 | 2020 |
| Peptide bond mimicry by (E)-alkene and (Z)-fluoroalkene peptide isosteres: synthesis and bioevaluation of α-helical anti-HIV peptide analogues S Oishi, H Kamitani, Y Kodera, K Watanabe, K Kobayashi, T Narumi, ... Organic & biomolecular chemistry 7 (14), 2872-2877, 2009 | 123 | 2009 |
| 2′-Deoxy-4′-C-ethynyl-2-halo-adenosines active against drug-resistant human immunodeficiency virus type 1 variants A Kawamoto, E Kodama, SG Sarafianos, Y Sakagami, S Kohgo, K Kitano, ... The international journal of biochemistry & cell biology 40 (11), 2410-2420, 2008 | 117 | 2008 |
| Syntheses of 4‘-C-Ethynyl-β-d-arabino- and 4‘-C-Ethynyl-2‘-deoxy-β-d-ribo-pentofuranosylpyrimidines and -purines and Evaluation of Their Anti-HIV Activity H Ohrui, S Kohgo, K Kitano, S Sakata, E Kodama, K Yoshimura, ... Journal of medicinal chemistry 43 (23), 4516-4525, 2000 | 117 | 2000 |
| Amino acid mutation N348I in the connection subdomain of human immunodeficiency virus type 1 reverse transcriptase confers multiclass resistance to nucleoside and nonnucleoside … A Hachiya, EN Kodama, SG Sarafianos, MM Schuckmann, Y Sakagami, ... Journal of virology 82 (7), 3261-3270, 2008 | 114 | 2008 |
| Elvitegravir: a new HIV integrase inhibitor K Shimura, EN Kodama Antiviral Chemistry and Chemotherapy 20 (2), 79-85, 2009 | 110 | 2009 |
| Activity against human immunodeficiency virus type 1, intracellular metabolism, and effects on human DNA polymerases of 4′-ethynyl-2-fluoro-2′-deoxyadenosine H Nakata, M Amano, Y Koh, E Kodama, G Yang, CM Bailey, S Kohgo, ... Antimicrobial agents and chemotherapy 51 (8), 2701-2708, 2007 | 108 | 2007 |
| Current research on chronic active E pstein–B arr virus infection in J apan S Fujiwara, H Kimura, K Imadome, A Arai, E Kodama, T Morio, N Shimizu, ... Pediatrics International 56 (2), 159-166, 2014 | 102 | 2014 |
| 4′-Ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) inhibits HIV-1 reverse transcriptase with multiple mechanisms E Michailidis, AD Huber, EM Ryan, YT Ong, MD Leslie, KB Matzek, ... Journal of Biological Chemistry 289 (35), 24533-24548, 2014 | 101 | 2014 |
