Follow
Onuralp Soylemez
Onuralp Soylemez
Harvard Medical School
Verified email at broadinstitute.org
Title
Cited by
Cited by
Year
Local fitness landscape of the green fluorescent protein
KS Sarkisyan, DA Bolotin, MV Meer, DR Usmanova, AS Mishin, ...
Nature 533 (7603), 397-401, 2016
5522016
Structure and evolutionary history of a large family of NLR proteins in the zebrafish
K Howe, S Philipp, J Zielinski, T Wiehe, G Laird, J Marioni, O Soylemez, ...
bioRxiv, 2015
1112015
Estimating the rate of irreversibility in protein evolution
O Soylemez, FA Kondrashov
Genome Biology and Evolution 4 (12), 1213-1222, 2012
442012
Evidence for secondary-variant genetic burden and non-random distribution across biological modules in a recessive ciliopathy
M Kousi, O Söylemez, A Ozanturk, N Mourtzi, S Akle, I Jungreis, J Muller, ...
Nature genetics 52 (11), 1145-1150, 2020
342020
Massively parallel enzyme kinetics reveals the substrate recognition landscape of the metalloprotease ADAMTS13
K Colin, M Dai, O Soylemez, A Yee, K Desch, D Siemieniak, K Tomberg, ...
Proceedings of the National Academy of Sciences, 2015
262015
An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery
A Haghighi, JB Krier, A Toth-Petroczy, CA Cassa, NY Frank, ...
NPJ genomic medicine 3 (1), 21, 2018
242018
Low-frequency inherited complement receptor variants are associated with purpura fulminans
PK Bendapudi, S Nazeen, J Ryu, O Söylemez, A Robbins, B Rouaisnel, ...
Blood 143 (11), 1032-1044, 2024
22024
Evaluation and optimization of sequence-based gene regulatory deep learning models
AM Rafi, D Nogina, D Penzar, D Lee, D Lee, N Kim, S Kim, D Kim, Y Shin, ...
bioRxiv, 2023
22023
Protein language model rescue mutations highlight variant effects and structure in clinically relevant genes
O Soylemez, P Cordero
NeurIPS 2022, Workshop on Learning Meaningful Representations of Life, 2022
12022
Pathway-based rare variant burden analysis identifies a role for the complement system in an extreme phenotype of sepsis with coagulopathy
PK Bendapudi, S Nazeen, J Ryu, O Söylemez, B Rouaisnel, M Colling, ...
Medrxiv, 2022.02. 24.22271459, 2022
12022
Rare inherited defects of the complement system in purpura fulminans
P Bendapudi, J Ryu, O Soylemez, B Rouaisnel, M Colling, B Pasko, ...
Blood 136, 35-36, 2020
12020
Investigating Gene Expression Signatures and Cell-Type Composition Changes in Sickle Cell Disease Using Whole Blood Transcriptomics
AA Potdar, M Caponegro, O Soylemez, A Reddy, K Yu
Blood 140 (Supplement 1), 5403-5404, 2022
2022
Bayesian tensor factorization for predicting clinical outcomes using integrated human genetics evidence
O Soylemez
arXiv preprint arXiv:2207.12538, 2022
2022
Bayesian tensor factorization for predicting clinical outcomes using integrated human genetics evidence
O Soylemez
ICML 2022, Workshop on Computational Biology, 2022
2022
Appendix 1. Working Group Members
D An, S Akasha, U Ben-David, E Blackwell, R Bhattacharyya, A Biasella, ...
2016
On the prevalence and role of epistasis in shaping fitness within and between populations
O Söylemez
Universitat Pompeu Fabra, 2016
2016
The system can't perform the operation now. Try again later.
Articles 1–16