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Yusuke Hayashi
Yusuke Hayashi
Assistant professor, The University of Tokyo
Verified email at pse.t.u-tokyo.ac.jp - Homepage
Title
Cited by
Cited by
Year
Slow freezing process design for human induced pluripotent stem cells by modeling intracontainer variation
Y Hayashi, I Horiguchi, M Kino-oka, H Sugiyama
Computers & Chemical Engineering 132, 106597, 2020
202020
Model-based assessment of temperature profiles in slow freezing for human induced pluripotent stem cells
Y Hayashi, I Horiguchi, M Kino-oka, H Sugiyama
Computers & Chemical Engineering 144, 107150, 2021
152021
A heterothermic kinetic model of hydrogen absorption in metals with subsurface transport
S Ono, T Uchikoshi, Y Hayashi, Y Kitagawa, G Yeh, E Yamaguchi, ...
Metals 9, 1131, 2019
122019
Hybrid-model-based design of fill-freeze-thaw processes for human induced pluripotent stem cells considering productivity and quality
Y Hayashi, M Kino-oka, H Sugiyama
Computers & Chemical Engineering 156, 107566, 2022
82022
Computational screening of cryoprotective agents for regenerative medical products using quantum chemistry and molecular dynamics simulations
Y Hayashi, Y Nakajima, H Sugiyama
Cryobiology 100, 101-109, 2021
82021
A Dynamic and Probabilistic Design Space Determination Method for Mesenchymal Stem Cell Cultivation Processes
K Hirono, I A. Udugama, Y Hayashi, M Kino-oka, H Sugiyama
Industrial & Engineering Chemistry Research 61, 7009-7019, 2022
62022
Impact of solvent selection on batch and flow syntheses for heterogeneous hydrogenation in drug substance manufacturing: A model-based analysis
J Kim, Y Hayashi, S Badr, H Nakanishi, H Sugiyama
Chemical Engineering Research and Design 189, 156-166, 2023
22023
An agent-based model for cost-effectiveness analysis in the manufacture of allogeneic human induced pluripotent cells in Japan
Y Hayashi, K Oishi, H Sugiyama
Computer Aided Chemical Engineering 49, 2203-2208, 2022
22022
The role of process systems engineering in applying quality by design (QbD) in mesenchymal stem cell production
IA Udugama, S Badr, K Hirono, BX Scholz, Y Hayashi, M Kino-oka, ...
Computers & Chemical Engineering 172, 108144, 2023
12023
A multilayered approach to scale-up forced convection-based freezing of human induced pluripotent stem cells
BX Scholz, Y Hayashi, IA Udugama, M Kino-oka, H Sugiyama
Computers & Chemical Engineering 163, 107851, 2022
12022
Design Space Determination of Mesenchymal Stem Cell Cultivation by Dynamic Modeling under Uncertainty
K Hirono, IA Udugama, Y Hayashi, M Kino-oka, H Sugiyama
Computer Aided Chemical Engineering 51, 721-726, 2022
12022
Multiobjective Dynamic Optimization of Slow Freezing Processes for Human Induced Pluripotent Stem Cells by Modeling Intracontainer Condition
Y Hayashi, I Horiguchi, M Kino-oka, H Sugiyama
Computer Aided Chemical Engineering 48, 265-270, 2020
12020
Integrated white-box models for designing freezing processes of human induced pluripotent stem cells considering diversity within a container
Y Hayashi, I Horiguchi, M Kino-oka, M Hirao, H Sugiyama
Computer Aided Chemical Engineering 46, 877-882, 2019
12019
Computer-aided exploration of multiobjective optimal temperature profiles in slow freezing for human induced pluripotent stem cells
Y Hayashi, Y Uno, M Kino-Oka, H Sugiyama
Cryobiology, 104885, 2024
2024
A Comprehensive Design Approach for Injectable Manufacturing Processes considering New Technologies and Operational Aspects
M Yamada, S Badr, Y Hayashi, K Zenitani, K Kubota, H Nakanishi, ...
Journal of Chemical Engineering of Japan 56 (1), 2201310, 2023
2023
A Systems Evaluation Model for the Development of Companion Diagnostics and Associated Molecularly Targeted Therapies
K Okamura, H Tsuchiya, R Hamada, Y Hayashi, S Badr, S Ohta, ...
Journal of Pharmaceutical Innovation 18 (4), 2265-2276, 2023
2023
Indicator-Based Supply Stability Analysis of Pharmaceutical Excipients: Method and Application
K Nemoto, Y Hayashi, H Sugiyama
2023 AIChE Annual Meeting, 2023
2023
Hybrid Modeling with Phase Contrast Microscopy Images for the Design of Mesenchymal Stem Cell Cultivation Processes
K Hirono, Y Hayashi, IA Udugama, MR Gaddem, Y Takemoto, R Kato, ...
2023 AIChE Annual Meeting, 2023
2023
Model-Based Design of the Next-Generation Decontamination Technology for Sterile Manufacturing
MR Gaddem, Y Hayashi, H Futamura, K Kawasaki, H Sugiyama
2023 AIChE Annual Meeting, 2023
2023
A Multilayered Approach to Continuous Freezing Process Design for Human Induced Pluripotent Stem Cells
Y Hayashi, B Scholz, H Sugiyama
2023 AIChE Annual Meeting, 2023
2023
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