Generation of T cells from human embryonic stem cell-derived hematopoietic zones F Timmermans, I Velghe, L Vanwalleghem, M De Smedt, ... The Journal of Immunology 182 (11), 6879-6888, 2009 | 249 | 2009 |
Defective CD4+CD25+regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-γ H Kelchtermans, B De Klerck, T Mitera, M Van Balen, D Bullens, A Billiau, ... Arthritis Res Ther 7, 1-14, 2005 | 225 | 2005 |
CD27 defines phenotypically and functionally different human NK cell subsets M Vossen, M Matmati, KML Hertoghs, PA Baars, MR Gent, G Leclercq, ... The Journal of Immunology 180 (6), 3739-3745, 2008 | 210 | 2008 |
Differential effects of interleukin-15 and interleukin-2 on differentiation of bipotential T/natural killer progenitor cells. G Leclercq, V Debacker, M De Smedt, J Plum The Journal of experimental medicine 184 (2), 325-336, 1996 | 209 | 1996 |
Activated CD4+ CD25+ regulatory T cells inhibit osteoclastogenesis and collagen-induced arthritis H Kelchtermans, L Geboes, T Mitera, D Huskens, G Leclercq, P Matthys Annals of the Rheumatic Diseases 68 (5), 744-750, 2009 | 185 | 2009 |
Interleukin-7 is a critical growth factor in early human T-cell development J Plum, M De Smedt, G Leclercq, B Verhasselt, B Vandekerckhove | 182 | 1996 |
Mouse TCRαβ+ CD8αα intraepithelial lymphocytes express genes that down-regulate their antigen reactivity and suppress immune responses TL Denning, S Granger, D Mucida, R Graddy, G Leclercq, W Zhang, ... The Journal of Immunology 178 (7), 4230-4239, 2007 | 171 | 2007 |
A Role for cis Interaction between the Inhibitory Ly49A receptor and MHC class I for natural killer cell education A Chalifour, L Scarpellino, J Back, P Brodin, E Devèvre, F Gros, F Lévy, ... Immunity 30 (3), 337-347, 2009 | 166 | 2009 |
β-Glucan microparticles are good candidates for mucosal antigen delivery in oral vaccination R De Smet, T Demoor, S Verschuere, M Dullaers, GR Ostroff, G Leclercq, ... Journal of controlled release 172 (3), 671-678, 2013 | 160 | 2013 |
An early decrease in Notch activation is required for human TCR-αβ lineage differentiation at the expense of TCR-γδ T cells I Van de Walle, G De Smet, M De Smedt, B Vandekerckhove, G Leclercq, ... Blood, The Journal of the American Society of Hematology 113 (13), 2988-2998, 2009 | 146 | 2009 |
Active form of Notch imposes T cell fate in human progenitor cells M De Smedt, K Reynvoet, T Kerre, T Taghon, B Verhasselt, ... The Journal of Immunology 169 (6), 3021-3029, 2002 | 145 | 2002 |
KLRG1 binds cadherins and preferentially associates with SHIP-1 MS Tessmer, C Fugere, F Stevenaert, OV Naidenko, HJ Chong, ... International immunology 19 (4), 391-400, 2007 | 143 | 2007 |
Matrix metalloprotease 8-dependent extracellular matrix cleavage at the blood–CSF barrier contributes to lethality during systemic inflammatory diseases RE Vandenbroucke, E Dejonckheere, P Van Lint, D Demeestere, ... Journal of Neuroscience 32 (29), 9805-9816, 2012 | 130 | 2012 |
Specific Notch receptor–ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength I Van de Walle, E Waegemans, J De Medts, G De Smet, M De Smedt, ... Journal of Experimental Medicine 210 (4), 683-697, 2013 | 126 | 2013 |
Interactions of Ly49 family receptors with MHC class I ligands in trans and cis L Scarpellino, F Oeschger, P Guillaume, JD Coudert, F Lévy, G Leclercq, ... The Journal of Immunology 178 (3), 1277-1284, 2007 | 121 | 2007 |
Different thresholds of Notch signaling bias human precursor cells toward B-, NK-, monocytic/dendritic-, or T-cell lineage in thymus microenvironment M De Smedt, I Hoebeke, K Reynvoet, G Leclercq, J Plum Blood 106 (10), 3498-3506, 2005 | 117 | 2005 |
Characterization of distinct stages during the differentiation of human CD69+ CD3+ thymocytes and identification of thymic emigrants. D Vanhecke, G Leclercq, J Plum, B Vandekerckhove Journal of immunology (Baltimore, Md.: 1950) 155 (4), 1862-1872, 1995 | 117 | 1995 |
Human CD34+ fetal liver stem cells differentiate to T cells in a mouse thymic microenvironment J Plum, M De Smedt, MP Defresne, G Leclercq, B Vandekerckhove | 112 | 1994 |
Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions I Van de Walle, G De Smet, M Gärtner, M De Smedt, E Waegemans, ... Blood, The Journal of the American Society of Hematology 117 (17), 4449-4459, 2011 | 111 | 2011 |
T-, B-and NK-lymphoid, but not myeloid cells arise from human CD34+ CD38− CD7+ common lymphoid progenitors expressing lymphoid-specific genes I Hoebeke, M De Smedt, F Stolz, K Pike-Overzet, FJT Staal, J Plum, ... Leukemia 21 (2), 311-319, 2007 | 105 | 2007 |