PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rules M Egholm, O Buchardt, L Christensen, C Behrens, SM Freier, DA Driver, ... Nature 365 (6446), 566-568, 1993 | 2810 | 1993 |
Synthesis of peptide nucleic acid monomers containing the four natural nucleobases: thymine, cytosine, adenine, and guanine and their oligomerization KL Dueholm, M Egholm, C Behrens, L Christensen, HF Hansen, T Vulpius, ... The Journal of Organic Chemistry 59 (19), 5767-5773, 1994 | 491 | 1994 |
Engineered CHO cells for production of diverse, homogeneous glycoproteins Z Yang, S Wang, A Halim, MA Schulz, M Frodin, SH Rahman, ... Nature biotechnology 33 (8), 842-844, 2015 | 260 | 2015 |
Small-molecule agonists for the glucagon-like peptide 1 receptor LB Knudsen, D Kiel, M Teng, C Behrens, D Bhumralkar, JT Kodra, ... Proceedings of the National Academy of Sciences 104 (3), 937-942, 2007 | 248 | 2007 |
Glycoprotein labeling using engineered variants of galactose oxidase obtained by directed evolution JB Rannes, A Ioannou, SC Willies, G Grogan, C Behrens, SL Flitsch, ... Journal of the American Chemical Society 133 (22), 8436-8439, 2011 | 118 | 2011 |
Peptide nucleic acids containing adenine or guanine recognize thymine and cytosine in complementary DNA sequences M Egholm, C Behrens, L Christensen, RH Berg, PE Nielsen, O Buchardt Journal of the Chemical Society, Chemical Communications, 800-801, 1993 | 81 | 1993 |
Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor M Teng, MD Johnson, C Thomas, D Kiel, JN Lakis, T Kercher, S Aytes, ... Bioorganic & Medicinal Chemistry Letters 17 (19), 5472-5478, 2007 | 72 | 2007 |
GLUCAGON ANTAGONISTS/INVERSE AGONISTS AS Jorgensen, IT Christensen, JT Kodra, C Sams, C Behrens, P Madsen, ... US Patent 20,020,143,186, 2002 | 64 | 2002 |
Novel glucagon receptor antagonists with improved selectivity over the glucose-dependent insulinotropic polypeptide receptor JT Kodra, AS Jørgensen, B Andersen, C Behrens, CL Brand, ... Journal of medicinal chemistry 51 (17), 5387-5396, 2008 | 63 | 2008 |
An enantioselective ring expansion route leading to furanose and pyranose nucleosides featuring spirodiketopiperazines at the anomeric position LA Paquette, S Brand, C Behrens The Journal of Organic Chemistry 64 (6), 2010-2025, 1999 | 62 | 1999 |
Glucagon antagonists/inverse agonists J Lau, IT Christensen, P Madsen, P Bloch, C Behrens, JT Kodra, ... US Patent 6,881,746, 2005 | 61 | 2005 |
New β-alanine derivatives are orally available glucagon receptor antagonists J Lau, C Behrens, UG Sidelmann, LB Knudsen, B Lundt, C Sams, ... Journal of Medicinal Chemistry 50 (1), 113-128, 2007 | 59 | 2007 |
Modified Proteins C Behrens, PW Garibay, M Zundel US Patent App. 11/664,199, 2008 | 56 | 2008 |
Berg, RH, Kim, SK, Nordkn, B. & Nielsen, PE (1993) M Egholm, O Buchardt, L Christensen, C Behrens, SM Freier, DA Driver Nature 365, 556-568, 0 | 53 | |
Modified proteins C Behrens US Patent App. 12/439,221, 2010 | 51 | 2010 |
Synthesis of a Hoechst 32258 analogue amino acid building block for direct incorporation of a fluorescent, high-affinity DNA binding motif into peptides C Behrens, N Harrit, PE Nielsen Bioconjugate Chemistry 12 (6), 1021-1027, 2001 | 45 | 2001 |
PEGylated factor VII glycoforms NK Klausen, S Bjorn, C Behrens, PW Garibay US Patent 8,053,410, 2011 | 44 | 2011 |
Pegylated factor VII glycoforms N Klausen, S Bjorn, C Behrens, P Garibay US Patent App. 10/609,701, 2005 | 40 | 2005 |
Glucagon antagonists/inverse agonists J Lau, P Madsen, C Sams, C Behrens, J Vagner, IT Christensen, BF Lundt, ... US Patent 6,503,949, 2003 | 39 | 2003 |
Human glucagon receptor antagonists with thiazole cores. A novel series with superior pharmacokinetic properties P Madsen, JT Kodra, C Behrens, E Nishimura, CB Jeppesen, L Pridal, ... Journal of medicinal chemistry 52 (9), 2989-3000, 2009 | 38 | 2009 |