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Georgi K. Kanev
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Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ...
Nature communications 10 (1), 2674, 2019
2752019
KLIFS: a structural kinase-ligand interaction database
AJ Kooistra, GK Kanev, OPJ van Linden, R Leurs, IJP de Esch, C de Graaf
Nucleic acids research 44 (D1), D365-D371, 2016
1522016
The landscape of atypical and eukaryotic protein kinases
GK Kanev, C de Graaf, IJP de Esch, R Leurs, T Würdinger, BA Westerman, ...
Trends in pharmacological sciences 40 (11), 818-832, 2019
1142019
KLIFS: an overhaul after the first 5 years of supporting kinase research
GK Kanev, C de Graaf, BA Westerman, IJP de Esch, AJ Kooistra
Nucleic acids research 49 (D1), D562-D569, 2021
972021
Crowdsourced mapping of unexplored target space of kinase inhibitors
A Cichońska, B Ravikumar, RJ Allaway, F Wan, S Park, O Isayev, S Li, ...
Nature communications 12 (1), 3307, 2021
632021
PDEStrIAn: a phosphodiesterase structure and ligand interaction annotated database as a tool for structure-based drug design
C Jansen, AJ Kooistra, GK Kanev, R Leurs, IJP de Esch, C de Graaf
Journal of medicinal chemistry 59 (15), 7029-7065, 2016
602016
Predicting the target landscape of kinase inhibitors using 3D convolutional neural networks
GK Kanev, Y Zhang, AJ Kooistra, A Bender, R Leurs, D Bailey, ...
PLoS computational biology 19 (9), e1011301, 2023
32023
1.15 - Structural Chemogenomics Databases to Navigate Protein–Ligand Interaction Space
GK Kanev, AJ Kooistra, IJP de Esch, C de Graaf
Comprehensive Medicinal Chemistry III 1, 444-471, 2017
32017
To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?
Y Zheng, S Schroeder, GK Kanev, SS Botros, S William, ANA Sabra, ...
International journal of molecular sciences 24 (7), 6817, 2023
12023
A Real-world Toxicity Atlas Shows that Adverse Events of Combination Therapies Commonly Result in Additive Interactions
A Küçükosmanoglu, S Scoarta, M Houweling, N Spinu, T Wijnands, ...
Clinical Cancer Research 30 (8), 1685-1695, 2024
2024
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