| Distinct effector B cells induced by unregulated toll-like receptor 7 contribute to pathogenic responses in systemic lupus erythematosus SA Jenks, KS Cashman, E Zumaquero, UM Marigorta, AV Patel, X Wang, ... Immunity 49 (4), 725-739. e6, 2018 | 714 | 2018 |
| Sex-determining region Y box 4 is a transforming oncogene in human prostate cancer cells P Liu, S Ramachandran, M Ali Seyed, CD Scharer, N Laycock, WB Dalton, ... Cancer research 66 (8), 4011-4019, 2006 | 350 | 2006 |
| Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells CD Scharer, CD McCabe, M Ali-Seyed, MF Berger, ML Bulyk, CS Moreno Cancer research 69 (2), 709-717, 2009 | 233 | 2009 |
| Lactobacilli modulate epithelial cytoprotection through the Nrf2 pathway RM Jones, C Desai, TM Darby, L Luo, AA Wolfarth, CD Scharer, CS Ardita, ... Cell reports 12 (8), 1217-1225, 2015 | 201 | 2015 |
| Global DNA methylation remodeling accompanies CD8 T cell effector function CD Scharer, BG Barwick, BA Youngblood, R Ahmed, JM Boss The Journal of Immunology 191 (6), 3419-3429, 2013 | 196 | 2013 |
| NF-κB regulates PD-1 expression in macrophages APR Bally, P Lu, Y Tang, JW Austin, CD Scharer, R Ahmed, JM Boss The Journal of Immunology 194 (9), 4545-4554, 2015 | 174 | 2015 |
| Epigenetic programming underpins B cell dysfunction in human SLE CD Scharer, EL Blalock, T Mi, BG Barwick, SA Jenks, T Deguchi, ... Nature immunology 20 (8), 1071-1082, 2019 | 156 | 2019 |
| Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation BG Barwick, CD Scharer, APR Bally, JM Boss Nature immunology 17 (10), 1216-1225, 2016 | 139 | 2016 |
| IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation E Zumaquero, SL Stone, CD Scharer, SA Jenks, A Nellore, B Mousseau, ... Elife 8, e41641, 2019 | 137 | 2019 |
| PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program M Hashimoto, K Araki, MA Cardenas, P Li, RR Jadhav, HT Kissick, ... Nature 610 (7930), 173-181, 2022 | 123 | 2022 |
| Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs CD Scharer, BG Barwick, M Guo, APR Bally, JM Boss Nature communications 9 (1), 1698, 2018 | 116 | 2018 |
| Progressive upregulation of oxidative metabolism facilitates plasmablast differentiation to a T-independent antigen MJ Price, DG Patterson, CD Scharer, JM Boss Cell reports 23 (11), 3152-3159, 2018 | 115 | 2018 |
| EZH2 represses the B cell transcriptional program and regulates antibody-secreting cell metabolism and antibody production M Guo, MJ Price, DG Patterson, BG Barwick, RR Haines, AK Kania, ... The Journal of Immunology 200 (3), 1039-1052, 2018 | 111 | 2018 |
| T-bet transcription factor promotes antibody-secreting cell differentiation by limiting the inflammatory effects of IFN-γ on B cells SL Stone, JN Peel, CD Scharer, CA Risley, DA Chisolm, MD Schultz, B Yu, ... Immunity 50 (5), 1172-1187. e7, 2019 | 103 | 2019 |
| Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells CD Scharer, N Laycock, AO Osunkoya, S Logani, JF McDonald, ... Journal of translational medicine 6, 1-13, 2008 | 100 | 2008 |
| ATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in naïve SLE B cells CD Scharer, EL Blalock, BG Barwick, RR Haines, C Wei, I Sanz, JM Boss Scientific reports 6 (1), 27030, 2016 | 99 | 2016 |
| B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation BG Barwick, CD Scharer, RJ Martinez, MJ Price, AN Wein, RR Haines, ... Nature communications 9 (1), 1900, 2018 | 98 | 2018 |
| Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8+ T cells SL Hayward, CD Scharer, EK Cartwright, S Takamura, ZRT Li, JM Boss, ... Nature immunology 21 (3), 309-320, 2020 | 89 | 2020 |
| ZBTB32 is an early repressor of the CIITA and MHC class II gene expression during B cell differentiation to plasma cells HS Yoon, CD Scharer, P Majumder, CW Davis, R Butler, ... The Journal of Immunology 189 (5), 2393-2403, 2012 | 86 | 2012 |
| Signaling through the inhibitory Fc receptor FcγRIIB induces CD8+ T cell apoptosis to limit T cell immunity AB Morris, CR Farley, DF Pinelli, LE Adams, MS Cragg, JM Boss, ... Immunity 52 (1), 136-150. e6, 2020 | 80 | 2020 |
