| Cellular and molecular mechanisms of metformin: an overview B Viollet, B Guigas, NS Garcia, J Leclerc, M Foretz, F Andreelli Clinical science 122 (6), 253-270, 2012 | 1559 | 2012 |
| Metformin: from mechanisms of action to therapies M Foretz, B Guigas, L Bertrand, M Pollak, B Viollet Cell metabolism 20 (6), 953-966, 2014 | 754 | 2014 |
| Activation of AMP‐activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders B Viollet, M Foretz, B Guigas, S Horman, R Dentin, L Bertrand, L Hue, ... The Journal of physiology 574 (1), 41-53, 2006 | 513 | 2006 |
| AMP‐activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives B Viollet, B Guigas, J Leclerc, S Hébrard, L Lantier, R Mounier, F Andreelli, ... Acta physiologica 196 (1), 81-98, 2009 | 439 | 2009 |
| AMPK: Lessons from transgenic and knockout animals B Viollet, Y Athea, R Mounier, B Guigas, E Zarrinpashneh, S Horman, ... Frontiers in bioscience (Landmark edition) 14, 19, 2009 | 289 | 2009 |
| Metformin prevents high-glucose–induced endothelial cell death through a mitochondrial permeability transition-dependent process D Detaille, B Guigas, C Chauvin, C Batandier, E Fontaine, ... Diabetes 54 (7), 2179-2187, 2005 | 283 | 2005 |
| Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status X Stephenne, M Foretz, N Taleux, GC Van der Zon, E Sokal, L Hue, ... Diabetologia 54 (12), 3101-3110, 2011 | 248 | 2011 |
| The ROS production induced by a reverse-electron flux at respiratory-chain complex 1 is hampered by metformin C Batandier, B Guigas, D Detaille, M El-Mir, E Fontaine, M Rigoulet, ... Journal of bioenergetics and biomembranes 38 (1), 33-42, 2006 | 248 | 2006 |
| Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons MY El-Mir, D Detaille, R Gloria, M Delgado-Esteban, B Guigas, S Attia, ... Journal of Molecular Neuroscience 34 (1), 77-87, 2008 | 218 | 2008 |
| 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside and metformin inhibit hepatic glucose phosphorylation by an AMP-activated protein kinase–independent effect on glucokinase … B Guigas, L Bertrand, N Taleux, M Foretz, N Wiernsperger, D Vertommen, ... Diabetes 55 (4), 865-874, 2006 | 194 | 2006 |
| Role of AMP kinase and PPARδ in the regulation of lipid and glucose metabolism in human skeletal muscle DK Krämer, L Al-Khalili, B Guigas, Y Leng, PM Garcia-Roves, A Krook Journal of Biological Chemistry 282 (27), 19313-19320, 2007 | 188 | 2007 |
| Mitochondrial metabolism and type-2 diabetes: a specific target of metformin XM Leverve, B Guigas, D Detaille, C Batandier, EA Koceir, C Chauvin, ... Diabetes & metabolism 29 (4), 6S88-6S94, 2003 | 170 | 2003 |
| Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study B Guigas, D Detaille, C Chauvin, C Batandier, F De Oliveira, E Fontaine, ... Biochemical journal 382 (3), 877-884, 2004 | 169 | 2004 |
| AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B L Bertrand, A Ginion, C Beauloye, AD Hebert, B Guigas, L Hue, ... American Journal of Physiology-Heart and Circulatory Physiology 291 (1 …, 2006 | 147 | 2006 |
| Chronic helminth infection and helminth‐derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice L Hussaarts, N García‐Tardón, L van Beek, MM Heemskerk, S Haeberlein, ... The FASEB Journal 29 (7), 3027-3039, 2015 | 142 | 2015 |
| Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice JJ Geerling, MR Boon, GC van der Zon, SAA van den Berg, ... Diabetes 63 (3), 880-891, 2014 | 137 | 2014 |
| AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative phosphorylation by AICA riboside B Guigas, N Taleux, M Foretz, D Detaille, F Andreelli, B Viollet, L Hue Biochemical Journal 404 (3), 499-507, 2007 | 113 | 2007 |
| Gene expression analysis of mTOR pathway: association with human longevity WM Passtoors, M Beekman, J Deelen, R van der Breggen, AB Maier, ... Aging Cell 12 (1), 24-31, 2013 | 112 | 2013 |
| Obligatory role of membrane events in the regulatory effect of metformin on the respiratory chain function D Detaille, B Guigas, X Leverve, N Wiernsperger, P Devos Biochemical pharmacology 63 (7), 1259-1272, 2002 | 103 | 2002 |
| A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts N Van Leeuwen, G Nijpels, ML Becker, H Deshmukh, K Zhou, ... Diabetologia 55 (7), 1971-1977, 2012 | 102 | 2012 |
Louis HUEProfessor of Biochemistry, Louvain University Medical SchoolEmail yang diverifikasi di uclouvain.be
