| An update on obesity: Mental consequences and psychological interventions DT Chu, NTM Nguyet, VT Nga, NVT Lien, DD Vo, N Lien, VTN Ngoc, ... Diabetes & Metabolic Syndrome: Clinical Research & Reviews 13 (1), 155-160, 2019 | 184 | 2019 |
| Rationally designed small molecules that target both the DNA and RNA causing myotonic dystrophy type 1 L Nguyen, LM Luu, S Peng, JF Serrano, HYE Chan, SC Zimmerman Journal of the American Chemical Society 137 (44), 14180-14189, 2015 | 119 | 2015 |
| Targeting toxic RNAs that cause myotonic dystrophy type 1 (DM1) with a bisamidinium inhibitor CH Wong, L Nguyen, J Peh, LM Luu, JS Sanchez, SL Richardson, ... Journal of the American Chemical Society 136 (17), 6355-6361, 2014 | 112 | 2014 |
| Antibody therapy targeting RAN proteins rescues C9 ALS/FTD phenotypes in C9orf72 mouse model L Nguyen, F Montrasio, A Pattamatta, SK Tusi, O Bardhi, KD Meyer, ... Neuron 105 (4), 645-662. e11, 2020 | 87 | 2020 |
| Metformin inhibits RAN translation through PKR pathway and mitigates disease in C9orf72 ALS/FTD mice T Zu, S Guo, O Bardhi, DA Ryskamp, J Li, S Khoramian Tusi, ... Proceedings of the National Academy of Sciences 117 (31), 18591-18599, 2020 | 81 | 2020 |
| A Novel CUGexp·MBNL1 Inhibitor with Therapeutic Potential for Myotonic Dystrophy Type 1 AH Jahromi, L Nguyen, Y Fu, KA Miller, AM Baranger, SC Zimmerman ACS chemical biology 8 (5), 1037-1043, 2013 | 72 | 2013 |
| Repeat-associated non-ATG translation: molecular mechanisms and contribution to neurological disease L Nguyen, JD Cleary, LPW Ranum Annual review of neuroscience 42, 227-247, 2019 | 64 | 2019 |
| Developing bivalent ligands to target CUG triplet repeats, the causative agent of myotonic dystrophy type 1 AH Jahromi, Y Fu, KA Miller, L Nguyen, LM Luu, AM Baranger, ... Journal of medicinal chemistry 56 (23), 9471-9481, 2013 | 60 | 2013 |
| Metformin inhibits RAN translation through PKR pathway and mitigates disease in C9orf72 ALS/FTD mice GS Zu T, O Bardhi, DA Ryskamp, J Li, SK Tusi, A Engelbrecht, K Klippel, ... Proc Natl Acad Sci USA 117 (31), 18591-18599, 2020 | 45 | 2020 |
| A Potent Inhibitor of Protein Sequestration by Expanded Triplet (CUG) Repeats that Shows Phenotypic Improvements in a Drosophila Model of Myotonic Dystrophy LM Luu, L Nguyen, S Peng, JY Lee, HY Lee, CH Wong, PJ Hergenrother, ... ChemMedChem 11 (13), 1428-1435, 2016 | 45 | 2016 |
| Integrating display and delivery functionality with a cell penetrating peptide mimic as a scaffold for intracellular multivalent multitargeting Y Bai, L Nguyen, Z Song, S Peng, JY Lee, N Zheng, I Kapoor, LD Hagler, ... Journal of the American Chemical Society 138 (30), 9498-9507, 2016 | 36 | 2016 |
| Survival and motor phenotypes in FVB C9-500 ALS/FTD BAC transgenic mice reproduced by multiple labs L Nguyen, LA Laboissonniere, S Guo, F Pilotto, O Scheidegger, ... Neuron 108 (4), 784-796. e3, 2020 | 29 | 2020 |
| Small molecules that target the toxic RNA in myotonic dystrophy type 2 L Nguyen, JY Lee, CH Wong, SC Zimmerman ChemMedChem 9 (11), 2455-2462, 2014 | 29 | 2014 |
| The alternative initiation factor eIF2A plays key role in RAN translation of myotonic dystrophy type 2 CCUG• CAGG repeats SK Tusi, L Nguyen, K Thangaraju, J Li, JD Cleary, T Zu, LPW Ranum Human Molecular Genetics 30 (11), 1020-1029, 2021 | 16 | 2021 |
| Repeat length increases disease penetrance and severity in C9orf72 ALS/FTD BAC transgenic mice A Pattamatta, L Nguyen, HR Olafson, MM Scotti, LA Laboissonniere, ... Human Molecular Genetics 29 (24), 3900-3918, 2020 | 12 | 2020 |
| RAN proteins in neurodegenerative disease: Repeating themes and unifying therapeutic strategies S Guo, L Nguyen, LPW Ranum Current opinion in neurobiology 72, 160-170, 2022 | 10 | 2022 |
| E.; Baranger, AM; Hergenrother, PJ; Zimmerman, SC CH Wong, L Nguyen, J Peh, LM Luu, JS Sanchez, SL Richardson, ... J. Am. Chem. Soc 136 (17), 6355, 2014 | 8 | 2014 |
| Immunoassays for detection of ran proteins L Ranum, L Nguyen US Patent App. 16/650,016, 2020 | 4 | 2020 |
| Bisamidinium-based inhibitors for the treatment of myotonic dystrophy SC Zimmerman, LM Luu, LTT Nguyen US Patent 10,266,520, 2019 | 2 | 2019 |
| Detection of antibodies against ran proteins from serum and tissue lysates L Ranum, LA Laboissonniere, L Nguyen US Patent App. 17/761,764, 2022 | 1 | 2022 |
