| Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis JD Turner, RS Langley, KL Johnston, K Gentil, L Ford, B Wu, M Graham, ... Journal of Biological Chemistry 284 (33), 22364-22378, 2009 | 177 | 2009 |
| Macrofilaricidal Activity after Doxycycline Only Treatment of Onchocerca volvulus in an Area of Loa loa Co-Endemicity: A Randomized Controlled Trial JD Turner, N Tendongfor, M Esum, KL Johnston, RS Langley, L Ford, ... PLoS neglected tropical diseases 4 (4), e660, 2010 | 169 | 2010 |
| A survey of anthelmintic resistant nematode parasites in Scottish sheep flocks DJ Bartley, E Jackson, K Johnston, RL Coop, GBB Mitchell, J Sales, ... Veterinary parasitology 117 (1-2), 61-71, 2003 | 125 | 2003 |
| Wolbachia filarial interactions MJ Taylor, D Voronin, KL Johnston, L Ford Cellular microbiology 15 (4), 520-526, 2013 | 121 | 2013 |
| Wolbachia endosymbiotic bacteria of Brugia malayi mediate macrophage tolerance to TLR-and CD40-specific stimuli in a MyD88/TLR2-dependent manner JD Turner, RS Langley, KL Johnston, G Egerton, S Wanji, MJ Taylor The Journal of Immunology 177 (2), 1240-1249, 2006 | 102 | 2006 |
| Functional conservation of the lipid II biosynthesis pathway in the cell wall‐less bacteria Chlamydia and Wolbachia: why is lipid II needed? B Henrichfreise, A Schiefer, T Schneider, E Nzukou, C Poellinger, ... Molecular microbiology 73 (5), 913-923, 2009 | 91 | 2009 |
| Corallopyronin A Specifically Targets and Depletes Essential Obligate Wolbachia Endobacteria From Filarial Nematodes In Vivo A Schiefer, A Schmitz, TF Schäberle, S Specht, C Lämmer, KL Johnston, ... The Journal of infectious diseases 206 (2), 249-257, 2012 | 79 | 2012 |
| Short-course, high-dose rifampicin achieves Wolbachia depletion predictive of curative outcomes in preclinical models of lymphatic filariasis and onchocerciasis G Aljayyoussi, HE Tyrer, L Ford, H Sjoberg, N Pionnier, D Waterhouse, ... Scientific reports 7 (1), 1-11, 2017 | 75 | 2017 |
| Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis MJ Taylor, TW von Geldern, L Ford, MP Hübner, K Marsh, KL Johnston, ... Science translational medicine 11 (483), eaau2086, 2019 | 73 | 2019 |
| Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis KL Johnston, L Ford, I Umareddy, S Townson, S Specht, K Pfarr, ... International Journal for Parasitology: Drugs and Drug Resistance 4 (3), 278-286, 2014 | 71 | 2014 |
| AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis WD Hong, F Benayoud, GL Nixon, L Ford, KL Johnston, RH Clare, ... Proceedings of the National Academy of Sciences 116 (4), 1414-1419, 2019 | 68 | 2019 |
| Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes KL Johnston, B Wu, A Guimarães, L Ford, BE Slatko, MJ Taylor Parasites & vectors 3 (1), 1-10, 2010 | 65 | 2010 |
| Overcoming the challenges of drug discovery for neglected tropical diseases: The A· WOL experience KL Johnston, L Ford, MJ Taylor Journal of biomolecular screening 19 (3), 335-343, 2014 | 61 | 2014 |
| Development and Validation of a High-Throughput Anti-Wolbachia Whole-Cell Screen: A Route to Macrofilaricidal Drugs against Onchocerciasis and Lymphatic … RH Clare, DAN Cook, KL Johnston, L Ford, SA Ward, MJ Taylor Journal of biomolecular screening 20 (1), 64-69, 2015 | 59 | 2015 |
| Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides RH Clare, C Bardelle, P Harper, WD Hong, U Börjesson, KL Johnston, ... Nature communications 10 (1), 1-8, 2019 | 54 | 2019 |
| Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis JD Turner, R Sharma, G Al Jayoussi, HE Tyrer, J Gamble, L Hayward, ... Proceedings of the National Academy of Sciences 114 (45), E9712-E9721, 2017 | 54 | 2017 |
| Extensively duplicated and transcriptionally active recent lateral gene transfer from a bacterial Wolbachia endosymbiont to its host filarial nematode Brugia malayi P Ioannidis, KL Johnston, DR Riley, N Kumar, JR White, KT Olarte, S Ott, ... BMC genomics 14 (1), 1-17, 2013 | 52 | 2013 |
| Critical comparison of molecular genotyping methods for detection of drug-resistant Plasmodium falciparum LC Ranford-Cartwright, KL Johnston, AM Abdel-Muhsin, BK Khan, ... Transactions of the Royal Society of Tropical Medicine and Hygiene 96 (5 …, 2002 | 48 | 2002 |
| Wolbachia endosymbionts induce neutrophil extracellular trap formation in human onchocerciasis F Tamarozzi, JD Turner, N Pionnier, A Midgley, AF Guimaraes, ... Scientific reports 6 (1), 1-13, 2016 | 47 | 2016 |
| Requirement of lipid II biosynthesis for cell division in cell wall-less Wolbachia, endobacteria of arthropods and filarial nematodes J Vollmer, A Schiefer, T Schneider, K Jülicher, KL Johnston, MJ Taylor, ... International Journal of Medical Microbiology 303 (3), 140-149, 2013 | 46 | 2013 |
