| Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart A Hoshino, Y Mita, Y Okawa, M Ariyoshi, E Iwai-Kanai, T Ueyama, K Ikeda, ... Nature communications 4 (1), 2308, 2013 | 479 | 2013 |
| Replicative senescence of vascular smooth muscle cells enhances the calcification through initiating the osteoblastic transition R Nakano-Kurimoto, K Ikeda, M Uraoka, Y Nakagawa, K Yutaka, M Koide, ... American Journal of Physiology-Heart and Circulatory Physiology 297 (5 …, 2009 | 251 | 2009 |
| Angiotensin II induces circadian gene expression of clock genes in cultured vascular smooth muscle cells H Nonaka, N Emoto, K Ikeda, H Fukuya, MS Rohman, SB Raharjo, ... Circulation 104 (15), 1746-1748, 2001 | 228 | 2001 |
| Inhibition of p53 preserves Parkin-mediated mitophagy and pancreatic β-cell function in diabetes A Hoshino, M Ariyoshi, Y Okawa, S Kaimoto, M Uchihashi, K Fukai, ... Proceedings of the National Academy of Sciences 111 (8), 3116-3121, 2014 | 219 | 2014 |
| p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia A Hoshino, S Matoba, E Iwai-Kanai, H Nakamura, M Kimata, M Nakaoka, ... Journal of molecular and cellular cardiology 52 (1), 175-184, 2012 | 169 | 2012 |
| Paracrine osteogenic signals via bone morphogenetic protein-2 accelerate the atherosclerotic intimal calcification in vivo Y Nakagawa, K Ikeda, Y Akakabe, M Koide, M Uraoka, K Yutaka, ... Arteriosclerosis, thrombosis, and vascular biology 30 (10), 1908-1915, 2010 | 144 | 2010 |
| Pathophysiology of vascular calcification: pivotal role of cellular senescence in vascular smooth muscle cells DGA Burton, H Matsubara, K Ikeda Experimental gerontology 45 (11), 819-824, 2010 | 140 | 2010 |
| Molecular identification and characterization of novel membrane-bound metalloprotease, the soluble secreted form of which hydrolyzes a variety of vasoactive peptides K Ikeda, N Emoto, SB Raharjo, Y Nurhantari, K Saiki, M Yokoyama, ... Journal of Biological Chemistry 274 (45), 32469-32477, 1999 | 134 | 1999 |
| Molecular isolation and characterization of a soluble isoform of activated leukocyte cell adhesion molecule that modulates endothelial cell function K Ikeda, T Quertermous Journal of Biological Chemistry 279 (53), 55315-55323, 2004 | 97 | 2004 |
| p53 promotes cardiac dysfunction in diabetic mellitus caused by excessive mitochondrial respiration-mediated reactive oxygen species generation and lipid accumulation H Nakamura, S Matoba, E Iwai-Kanai, M Kimata, A Hoshino, M Nakaoka, ... Circulation: Heart Failure 5 (1), 106-115, 2012 | 92 | 2012 |
| Macrophages play a unique role in the plaque calcification by enhancing the osteogenic signals exerted by vascular smooth muscle cells K Ikeda, Y Souma, Y Akakabe, Y Kitamura, K Matsuo, Y Shimoda, ... Biochemical and biophysical research communications 425 (1), 39-44, 2012 | 90 | 2012 |
| p53 and TIGAR regulate cardiac myocyte energy homeostasis under hypoxic stress M Kimata, S Matoba, E Iwai-Kanai, H Nakamura, A Hoshino, M Nakaoka, ... American Journal of Physiology-Heart and Circulatory Physiology 299 (6 …, 2010 | 80 | 2010 |
| Glia maturation factor-γ is preferentially expressed in microvascular endothelial and inflammatory cells and modulates actin cytoskeleton reorganization K Ikeda, RK Kundu, S Ikeda, M Kobara, H Matsubara, T Quertermous Circulation research 99 (4), 424-433, 2006 | 78 | 2006 |
| Molecular identification and characterization of a novel nuclear protein whose expression is up-regulated in insulin-resistant animals K Ikeda, N Emoto, M Matsuo, M Yokoyama Journal of Biological Chemistry 278 (6), 3514-3520, 2003 | 77 | 2003 |
| MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by α1-adrenergic receptors T Ogata, D Naito, N Nakanishi, YK Hayashi, T Taniguchi, K Miyagawa, ... Proceedings of the National Academy of Sciences 111 (10), 3811-3816, 2014 | 71 | 2014 |
| Manipulation of cardiac phosphatidylinositol 3-kinase (PI3K)/Akt signaling by apoptosis regulator through modulating IAP expression (ARIA) regulates cardiomyocyte death during … Y Kitamura, M Koide, Y Akakabe, K Matsuo, Y Shimoda, Y Soma, T Ogata, ... Journal of biological chemistry 289 (5), 2788-2800, 2014 | 55 | 2014 |
| Prorenin induces ERK activation in endothelial cells to enhance neovascularization independently of the renin–angiotensin system M Uraoka, K Ikeda, Y Nakagawa, M Koide, Y Akakabe, ... Biochemical and biophysical research communications 390 (4), 1202-1207, 2009 | 54 | 2009 |
| Neuregulin-4 is an angiogenic factor that is critically involved in the maintenance of adipose tissue vasculature DB Nugroho, K Ikeda, AJ Barinda, DA Wardhana, K Yagi, K Miyata, ... Biochemical and biophysical research communications 503 (1), 378-384, 2018 | 42 | 2018 |
| Apoptosis regulator through modulating IAP expression (ARIA) controls the PI3K/Akt pathway in endothelial and endothelial progenitor cells M Koide, K Ikeda, Y Akakabe, Y Kitamura, T Ueyama, S Matoba, ... Proceedings of the National Academy of Sciences 108 (23), 9472-9477, 2011 | 42 | 2011 |
| Identification of ARIA regulating endothelial apoptosis and angiogenesis by modulating proteasomal degradation of cIAP-1 and cIAP-2 K Ikeda, R Nakano, M Uraoka, Y Nakagawa, M Koide, A Katsume, ... Proceedings of the National Academy of Sciences 106 (20), 8227-8232, 2009 | 40 | 2009 |
