| X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death SW Muchmore, M Sattler, H Liang, RP Meadows, JE Harlan, HS Yoon, ... Nature 381 (6580), 335-341, 1996 | 2045 | 1996 |
| Bcl-xL forms an ion channel in synthetic lipid membranes AJ Minn, P Vélez, SL Schendel, H Liang, SW Muchmore, SW Fesik, M Fill, ... Nature 385 (6614), 353-357, 1997 | 1180 | 1997 |
| Crystal structure of the biphenyl-cleaving extradiol dioxygenase from a PCB-degrading pseudomonad S Han, LD Eltis, KN Timmis, SW Muchmore, JT Bolin Science 270 (5238), 976-980, 1995 | 424 | 1995 |
| Identification of a novel regulatory domain in Bcl‐xL and Bcl‐2 BS Chang, AJ Minn, SW Muchmore, SW Fesik, CB Thompson The EMBO journal, 1997 | 410 | 1997 |
| The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to … B Kauppi, C Jakob, M Färnegårdh, J Yang, H Ahola, M Alarcon, ... Journal of Biological Chemistry 278 (25), 22748-22754, 2003 | 406 | 2003 |
| Molecular shape and medicinal chemistry: a perspective A Nicholls, GB McGaughey, RP Sheridan, AC Good, G Warren, M Mathieu, ... Journal of medicinal chemistry 53 (10), 3862-3886, 2010 | 330 | 2010 |
| Crystal structure and mutagenic analysis of the inhibitor-of-apoptosis protein survivin SW Muchmore, J Chen, C Jakob, D Zakula, ED Matayoshi, W Wu, ... Molecular cell 6 (1), 173-182, 2000 | 223 | 2000 |
| Crystal structure of recombinant human interleukin-1β at 2· 0 Å resolution BC Finzel, LL Clancy, DR Holland, SW Muchmore, KD Watenpaugh, ... Journal of molecular biology 209 (4), 779-791, 1989 | 211 | 1989 |
| Synthesis and evaluation of benzothiazole-based analogues as novel, potent, and selective fatty acid amide hydrolase inhibitors X Wang, K Sarris, K Kage, D Zhang, SP Brown, T Kolasa, C Surowy, ... Journal of medicinal chemistry 52 (1), 170-180, 2009 | 169 | 2009 |
| Application of belief theory to similarity data fusion for use in analog searching and lead hopping SW Muchmore, DA Debe, JT Metz, SP Brown, YC Martin, PJ Hajduk Journal of chemical information and modeling 48 (5), 941-948, 2008 | 166 | 2008 |
| Influenza neuraminidase inhibitors: structure-based design of a novel inhibitor series V Stoll, KD Stewart, CJ Maring, S Muchmore, V Giranda, YY Gu, G Wang, ... Biochemistry 42 (3), 718-727, 2003 | 166 | 2003 |
| Structure of a secreted aspartic protease from C. albicans complexed with a potent inhibitor: Implications for the design of antifungal agents C Abad‐Zapatero, R Goldman, SW Muchmore, C Hutchins, K Stewart, ... Protein Science 5 (4), 640-652, 1996 | 164 | 1996 |
| The crystal structure of a lysine 49 phospholipase A2 from the venom of the cottonmouth snake at 2.0-A resolution. DR Holland, LL Clancy, SW Muchmore, TJ Ryde, HM Einspahr, BC Finzel, ... Journal of Biological Chemistry 265 (29), 17649-17656, 1990 | 157 | 1990 |
| Crystal structure of ErmC ‘, an rRNA methyltransferase which mediates antibiotic resistance in bacteria DE Bussiere, SW Muchmore, CG Dealwis, G Schluckebier, VL Nienaber, ... Biochemistry 37 (20), 7103-7112, 1998 | 153 | 1998 |
| POSIT: flexible shape-guided docking for pose prediction BP Kelley, SP Brown, GL Warren, SW Muchmore Journal of Chemical Information and Modeling 55 (8), 1771-1780, 2015 | 130 | 2015 |
| High-throughput calculation of protein− ligand binding affinities: Modification and adaptation of the MM-PBSA protocol to enterprise grid computing SP Brown, SW Muchmore Journal of chemical information and modeling 46 (3), 999-1005, 2006 | 120 | 2006 |
| Automated crystal mounting and data collection for protein crystallography SW Muchmore, J Olson, R Jones, J Pan, M Blum, J Greer, SM Merrick, ... Structure 8 (12), R243-R246, 2000 | 120 | 2000 |
| Healthy skepticism: assessing realistic model performance SP Brown, SW Muchmore, PJ Hajduk Drug discovery today 14 (7-8), 420-427, 2009 | 118 | 2009 |
| Large-scale application of high-throughput molecular mechanics with Poisson− Boltzmann surface area for routine physics-based scoring of protein− ligand complexes SP Brown, SW Muchmore Journal of medicinal chemistry 52 (10), 3159-3165, 2009 | 116 | 2009 |
| A unified, probabilistic framework for structure-and ligand-based virtual screening SL Swann, SP Brown, SW Muchmore, H Patel, P Merta, J Locklear, ... Journal of medicinal chemistry 54 (5), 1223-1232, 2011 | 105 | 2011 |
Craig ThompsonMemorial Sloan Kettering Cancer CenterEmail yang diverifikasi di mskcc.org
