Thomas Dorlo
Thomas Dorlo
Pharmacometrician, Antoni van Leeuwenhoek Hospital / Netherlands Cancer Institute
Verified email at - Homepage
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Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis
TPC Dorlo, M Balasegaram, JH Beijnen, PJ de Vries
Journal of Antimicrobial Chemotherapy 67 (11), 2576-2597, 2012
Increasing failure of miltefosine in the treatment of Kala-azar in Nepal and the potential role of parasite drug resistance, reinfection, or noncompliance
S Rijal, B Ostyn, S Uranw, K Rai, NR Bhattarai, TPC Dorlo, JH Beijnen, ...
Clinical Infectious Diseases 56 (11), 1530-1538, 2013
Pharmacokinetics of miltefosine in Old World cutaneous leishmaniasis patients
TPC Dorlo, PPAM van Thiel, ADR Huitema, RJ Keizer, HJC de Vries, ...
Antimicrobial agents and chemotherapy 52 (8), 2855-2860, 2008
Failure of miltefosine in visceral leishmaniasis is associated with low drug exposure
TPC Dorlo, S Rijal, B Ostyn, PJ de Vries, R Singh, N Bhattarai, S Uranw, ...
The Journal of infectious diseases 210 (1), 146-153, 2014
LeishMan recommendations for treatment of cutaneous and mucosal leishmaniasis in travelers, 2014
J Blum, P Buffet, L Visser, G Harms, MS Bailey, E Caumes, J Clerinx, ...
Journal of travel medicine 21 (2), 116-129, 2014
Optimal dosing of miltefosine in children and adults with visceral leishmaniasis
TPC Dorlo, ADR Huitema, JH Beijnen, PJ de Vries
Antimicrobial agents and chemotherapy 56 (7), 3864-3872, 2012
Safety and efficacy of single dose versus multiple doses of AmBisomeŽ for treatment of visceral leishmaniasis in eastern Africa: a randomised trial
EAG Khalil, T Weldegebreal, BM Younis, R Omollo, AM Musa, W Hailu, ...
PLoS Negl Trop Dis 8 (1), e2613, 2014
Failure of miltefosine treatment for visceral leishmaniasis in children and men in South-East Asia
B Ostyn, E Hasker, TPC Dorlo, S Rijal, S Sundar, JC Dujardin, M Boelaert
PLoS One 9 (6), e100220, 2014
Efficacy and safety of AmBisome in combination with sodium stibogluconate or miltefosine and miltefosine monotherapy for African visceral leishmaniasis: phase II randomized trial
M Wasunna, S Njenga, M Balasegaram, N Alexander, R Omollo, ...
PLoS neglected tropical diseases 10 (9), e0004880, 2016
Development and validation of a quantitative assay for the measurement of miltefosine in human plasma by liquid chromatography–tandem mass spectrometry
TPC Dorlo, MJX Hillebrand, H Rosing, TA Eggelte, PJ de Vries, ...
Journal of Chromatography B 865 (1-2), 55-62, 2008
Safety and efficacy of miltefosine alone and in combination with sodium stibogluconate and liposomal amphotericin B for the treatment of primary visceral leishmaniasis in East …
R Omollo, N Alexander, T Edwards, EAG Khalil, BM Younis, AA Abuzaid, ...
Trials 12 (1), 1-10, 2011
Systematic review of biomarkers to monitor therapeutic response in leishmaniasis
AE Kip, M Balasegaram, JH Beijnen, JHM Schellens, PJ de Vries, ...
Antimicrobial agents and chemotherapy 59 (1), 1-14, 2015
A poor-quality generic drug for the treatment of visceral leishmaniasis: a case report and appeal
TPC Dorlo, TA Eggelte, GJ Schoone, PJ de Vries, JH Beijnen
PLoS Negl Trop Dis 6 (5), e1544, 2012
Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adults
P Byakika-Kibwika, M Lamorde, V Okaba-Kayom, H Mayanja-Kizza, ...
Journal of antimicrobial chemotherapy 67 (5), 1217-1223, 2012
Severe encephalopathy and polyneuropathy induced by dichloroacetate
D Brandsma, TPC Dorlo, JH Haanen, JH Beijnen, W Boogerd
Journal of neurology 257 (12), 2099-2100, 2010
Characterization and identification of suspected counterfeit miltefosine capsules
TPC Dorlo, TA Eggelte, PJ de Vries, JH Beijnen
Analyst 137 (5), 1265-1274, 2012
Volumetric absorptive microsampling (VAMS) as an alternative to conventional dried blood spots in the quantification of miltefosine in dried blood samples
AE Kip, KC Kiers, H Rosing, JHM Schellens, JH Beijnen, TPC Dorlo
Journal of pharmaceutical and biomedical analysis 135, 160-166, 2017
Pentamidine dosage: a base/salt confusion
TPC Dorlo, PA Kager
PLoS Negl Trop Dis 2 (5), e225, 2008
Pharmacokinetics of miltefosine in children and adults with cutaneous leishmaniasis
M del Mar Castro, MA Gomez, AE Kip, A Cossio, E Ortiz, A Navas, ...
Antimicrobial agents and chemotherapy 61 (3), 2017
Translational pharmacokinetic modelling and simulation for the assessment of duration of contraceptive use after treatment with miltefosine
TPC Dorlo, M Balasegaram, MA Lima, PJ de Vries, JH Beijnen, ...
Journal of antimicrobial chemotherapy 67 (8), 1996-2004, 2012
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