| Reversal of bone loss in mice by nongenotropic signaling of sex steroids S Kousteni, JR Chen, T Bellido, L Han, AA Ali, CA O'Brien, L Plotkin, Q Fu, ... Science 298 (5594), 843-846, 2002 | 536 | 2002 |
| Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids RS Weinstein, JR Chen, CC Powers, SA Stewart, RD Landes, T Bellido, ... The Journal of clinical investigation 109 (8), 1041-1048, 2002 | 480 | 2002 |
| Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids S Kousteni, L Han, JR Chen, M Almeida, LI Plotkin, T Bellido, ... The Journal of clinical investigation 111 (11), 1651-1664, 2003 | 356 | 2003 |
| Transient versus sustained phosphorylation and nuclear accumulation of ERKs underlie anti-versus pro-apoptotic effects of estrogens JR Chen, LI Plotkin, JI Aguirre, L Han, RL Jilka, S Kousteni, T Bellido, ... Journal of biological chemistry 280 (6), 4632-4638, 2005 | 215 | 2005 |
| Dietary‐induced serum phenolic acids promote bone growth via p38 MAPK/β‐catenin canonical Wnt signaling JR Chen, OP Lazarenko, X Wu, J Kang, ML Blackburn, K Shankar, ... Journal of Bone and Mineral Research 25 (11), 2399-2411, 2010 | 144 | 2010 |
| The health implications of soy infant formula TM Badger, JM Gilchrist, RT Pivik, A Andres, K Shankar, JR Chen, ... The American journal of clinical nutrition 89 (5), 1668S-1672S, 2009 | 134 | 2009 |
| A role for ethanol‐induced oxidative stress in controlling lineage commitment of mesenchymal stromal cells through inhibition of Wnt/β‐catenin signaling JR Chen, OP Lazarenko, K Shankar, ML Blackburn, TM Badger, MJ Ronis Journal of Bone and Mineral Research 25 (5), 1117-1127, 2010 | 129 | 2010 |
| Obesity reduces bone density associated with activation of PPARγ and suppression of Wnt/β-catenin in rapidly growing male rats JR Chen, OP Lazarenko, X Wu, Y Tong, ML Blackburn, K Shankar, ... PloS one 5 (10), e13704, 2010 | 128 | 2010 |
| Maternal obesity promotes a proinflammatory signature in rat uterus and blastocyst K Shankar, Y Zhong, P Kang, F Lau, ML Blackburn, JR Chen, ... Endocrinology 152 (11), 4158-4170, 2011 | 120 | 2011 |
| Nongenotropic, anti-apoptotic signaling of 1α, 25 (OH) 2-vitamin D3 and analogs through the ligand binding domain of the vitamin D receptor in osteoblasts and osteocytes … AM Vertino, CM Bula, JR Chen, M Almeida, L Han, T Bellido, S Kousteni, ... Journal of Biological Chemistry 280 (14), 14130-14137, 2005 | 115 | 2005 |
| Protective effects of estradiol on ethanol-induced bone loss involve inhibition of reactive oxygen species generation in osteoblasts and downstream activation of the … JR Chen, K Shankar, S Nagarajan, TM Badger, MJJ Ronis Journal of Pharmacology and Experimental Therapeutics 324 (1), 50-59, 2008 | 97 | 2008 |
| Inhibition of NADPH oxidases prevents chronic ethanol-induced bone loss in female rats JR Chen, OP Lazarenko, K Shankar, ML Blackburn, CK Lumpkin, ... Journal of Pharmacology and Experimental Therapeutics 336 (3), 734-742, 2011 | 72 | 2011 |
| Ethanol impairs estrogen receptor signaling resulting in accelerated activation of senescence pathways, whereas estradiol attenuates the effects of ethanol in osteoblasts JR Chen, OP Lazarenko, RL Haley, ML Blackburn, TM Badger, MJ Ronis Journal of Bone and Mineral Research 24 (2), 221-230, 2009 | 72 | 2009 |
| Feeding blueberry diets in early life prevent senescence of osteoblasts and bone loss in ovariectomized adult female rats J Zhang, OP Lazarenko, ML Blackburn, K Shankar, TM Badger, ... PLoS One 6 (9), e24486, 2011 | 70 | 2011 |
| Estradiol protects against ethanol-induced bone loss by inhibiting up-regulation of receptor activator of nuclear factor-κB ligand in osteoblasts JR Chen, RL Haley, M Hidestrand, K Shankar, X Liu, CK Lumpkin, ... Journal of Pharmacology and Experimental Therapeutics 319 (3), 1182-1190, 2006 | 65 | 2006 |
| Long‐term antiepileptic drug administration during early life inhibits hippocampal neurogenesis in the developing brain J Chen, F Cai, J Cao, X Zhang, S Li Journal of neuroscience research 87 (13), 2898-2907, 2009 | 63 | 2009 |
| Phenolic acids are in vivo atheroprotective compounds appearing in the serum of rats after blueberry consumption C Xie, J Kang, JR Chen, S Nagarajan, TM Badger, X Wu Journal of agricultural and food chemistry 59 (18), 10381-10387, 2011 | 60 | 2011 |
| Chronic ethanol consumption leads to disruption of vitamin D3 homeostasis associated with induction of renal 1, 25 dihydroxyvitamin D3-24-hydroxylase (CYP24A1) K Shankar, X Liu, R Singhal, JR Chen, S Nagarajan, TM Badger, ... Endocrinology 149 (4), 1748-1756, 2008 | 60 | 2008 |
| Effects of nutrition and alcohol consumption on bone loss MJJ Ronis, K Mercer, JR Chen Current osteoporosis reports 9, 53-59, 2011 | 59 | 2011 |
| Inhibition of fetal bone development through epigenetic down‐regulation of HoxA10 in obese rats fed high‐fat diet JR Chen, J Zhang, OP Lazarenko, P Kang, ML Blackburn, MJJ Ronis, ... The FASEB Journal 26 (3), 1131-1141, 2012 | 58 | 2012 |
